Pub. Date : 2015 Nov
PMID : 26807121
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study investigated the synergistic effect of the combined use of the ROCK inhibitor fasudil and a COX-2 inhibitor celecoxib on spinal cord injury in a rat model established by transecting the right half of the spinal cord at T11. | Celecoxib | prostaglandin-endoperoxide synthase 2 | Rattus norvegicus |
| 2 | Results demonstrated that the combined use of celecoxib and fasudil significantly decreased COX-2 and Rho kinase II expression surrounding the lesion site in rats with spinal cord injury, improved the pathomorphology of the injured spinal cord, and promoted the recovery of motor function. | Celecoxib | prostaglandin-endoperoxide synthase 2 | Rattus norvegicus |