Title : Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome.

Pub. Date : 2021 Apr

PMID : 33184783






1 Functional Relationships(s)
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1 We hypothesized that previously reported neuroprotection of celecoxib, a selective inhibitor of cyclooxygenase-2, in transient middle cerebral artery occlusion (tMCAO) model, relies on the ER stress decrease. Celecoxib prostaglandin-endoperoxide synthase 2 Rattus norvegicus