Wortmannin

caspase 3 ; Homo sapiens







34 Article(s)
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1 26749462 6-Gingerol Mediates its Anti Tumor Activities in Human Oral and Cervical Cancer Cell Lines through Apoptosis and Cell Cycle Arrest. 2016 Apr 1
2 27138223 PI3K/AKT Signaling Pathway Is Essential for Survival of Induced Pluripotent Stem Cells. 2016 1
3 25344912 Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway. 2014 Nov 30 1
4 23837937 Sphingosine 1-phosphate attenuates peroxide-induced apoptosis in HaCaT cells cultured in vitro. 2013 Aug 1
5 24020912 Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis. 2013 1
6 22112812 Gonadotropin-releasing hormone-I or -II interacts with IGF-I/Akt but not connexin 43 in human granulosa cell apoptosis. 2012 Feb 1
7 21300060 Down-regulation of PKHD1 induces cell apoptosis through PI3K and NF-κB pathways. 2011 Apr 15 1
8 20814073 ERK 1/2 and PI-3 kinase pathways as a potential mechanism of ghrelin action on cell proliferation and apoptosis in the porcine ovarian follicular cells. 2010 Aug 1
9 21042768 Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation. 2010 Dec 1
10 19541408 Wortmannin potentiates roscovitine-induced growth inhibition in human solid tumor cells by repressing PI3K/Akt pathway. 2009 Dec 28 1
11 17935137 Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. 2008 Jan 15 1
12 18256309 Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. 2008 Apr 1
13 18929542 Up-regulation of IAPs by PI-3K: a cell survival signal-mediated anti-apoptotic mechanism. 2008 Dec 12 1
14 17656415 Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway. 2007 Oct 1
15 17901567 Inhibitory effects of 1,25-dihydroxyvitamin D3 and its low-calcemic analogues on staurosporine-induced apoptosis. 2007 Jul-Aug 1
16 19771269 Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3-kinase inhibition in the human cervical cancer cell-line. 2006 Apr 1
17 15632127 Inhibition of Src-like kinases reveals Akt-dependent and -independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival. 2005 Mar 11 1
18 15993382 Erythropoietin attenuated high glucose-induced apoptosis in cultured human aortic endothelial cells. 2005 Aug 19 1
19 15033167 Regulation of caspase activation in axotomized retinal ganglion cells. 2004 Mar 1
20 15142122 Hydrogen peroxide in the Burkitt's lymphoma cell line Raji provides protection against arsenic trioxide-induced apoptosis via the phosphoinositide-3 kinase signalling pathway. 2004 May 1
21 11804874 Monocyte survival factors induce Akt activation and suppress caspase-3. 2002 Feb 1
22 11835396 Insulin-like growth factor-1 protects peroxynitrite-induced cell death by preventing cytochrome c-induced caspase-3 activation. 2002 1
23 12032677 Control of ceramide-induced apoptosis by IGF-1: involvement of PI-3 kinase, caspase-3 and catalase. 2002 Jun 1
24 12060639 Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line. 2002 Jun 1
25 11230338 Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells. 2001 Feb 1
26 10658194 Multiple polyphosphoinositide pathways regulate apoptotic signalling in a dorsal root ganglion derived cell line. 2000 Jan 1 4
27 10850726 Significance of tau phosphorylation and protein kinase regulation in the pathogenesis of Alzheimer disease. 2000 1
28 10873605 IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress. 2000 Jun 24 1
29 10383455 Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway. 1999 Jul 2 1
30 10537063 Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons. 1999 Nov 1
31 10723061 Differential responses of oligodendrocytes to tumor necrosis factor and other pro-apoptotic agents: role of ceramide in apoptosis. 1999 Feb 15 2
32 10200474 Wortmannin enhances activation of CPP32 (Caspase-3) induced by TNF or anti-Fas. 1998 Apr 6
33 9125129 Wortmannin enhances CPP32-like activity during neuronal differentiation of P19 embryonal carcinoma cells induced by retinoic acid. 1997 Mar 6 2
34 8663611 Activation of the CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-xL. 1996 Jul 26 1