Title : IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress.

Pub. Date : 2000 Jun 24

PMID : 10873605






1 Functional Relationships(s)
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1 Furthermore, IGF-1 appeared to reduce the activation of a number of early components in the apoptotic pathway in a wortmannin dependent manner including the osmotic stress-induced perturbation in mitochondrial membrane potential, cleavage and activation of caspase-3 and DNA fragmentation. Wortmannin caspase 3 Homo sapiens