Title : Inhibition of Src-like kinases reveals Akt-dependent and -independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival.

Pub. Date : 2005 Mar 11

PMID : 15632127






1 Functional Relationships(s)
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1 In addition, IGF-I activated Akt while inhibiting caspase-3 activation, and these effects were reversed by the PI3K inhibitors LY 294002 and wortmannin, but not by the MEK1 inhibitor PD 98059. Wortmannin caspase 3 Homo sapiens