Title : A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice.

Pub. Date : 2017 Jan 3

PMID : 27888812

1 Functional Relationships(s)
Compound Name
Protein Name
1 SLNT induced apoptosis by activating Caspase-3 via both intrinsic and extrinsic pathways, which presented as the activation of Caspases-9 and -8, upregulation of cytochrome c and the Bax/Bcl-2 ratio, downregulation of NF-kappaB, and overproduction of ROS and TNF-alpha in vitro and in vivo. ros caspase 3 Homo sapiens