Title : Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis.

Pub. Date : 2013 Jul 9

PMID : 23834359






2 Functional Relationships(s)
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1 We also demonstrate that caspase-3-deficient MEFs are less sensitive to intrinsic cell death stimulation, yet have higher ROS production. ros caspase 3 Homo sapiens
2 After activation by caspase-9, caspase-3 inhibits ROS production and is required for efficient execution of apoptosis, while effector caspase-7 is required for apoptotic cell detachment. ros caspase 3 Homo sapiens