| 1 |
33315368 | Two-Substrate Glyoxalase I Mechanism: A Quantum Mechanics/Molecular Mechanics Study. | 2021 Jan 4 |
1 |
| 2 |
33360689 | Genomic GLO1 deletion modulates TXNIP expression, glucose metabolism, and redox homeostasis while accelerating human A375 malignant melanoma tumor growth. | 2021 Feb |
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| 3 |
31879183 | Recent advances in the discovery and development of glyoxalase I inhibitors. | 2020 Feb 15 |
2 |
| 4 |
32011880 | Quantum Mechanics/Molecular Mechanics Study of the Reaction Mechanism of Glyoxalase I. | 2020 Feb 17 |
2 |
| 5 |
32466621 | Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro and In Vivo. | 2020 May 26 |
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| 6 |
32524572 | Spectrophotometric Method for Determining Glyoxalase 1 Activity in Cerebral Cavernous Malformation (CCM) Disease. | 2020 |
6 |
| 7 |
32640624 | Adeno-Associated Viral Transfer of Glyoxalase-1 Blunts Carbonyl and Oxidative Stresses in Hearts of Type 1 Diabetic Rats. | 2020 Jul 6 |
1 |
| 8 |
33379155 | Interplay among Oxidative Stress, Methylglyoxal Pathway and S-Glutathionylation. | 2020 Dec 28 |
1 |
| 9 |
29385039 | Glyoxalases in Urological Malignancies. | 2018 Jan 31 |
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| 10 |
30179128 | Role of Methylglyoxal in Diabetic Cardiovascular and Kidney Diseases: Insights from Basic Science for Application into Clinical Practice. | 2018 |
2 |
| 11 |
27956549 | Loss of Glyoxalase 1 Induces Compensatory Mechanism to Achieve Dicarbonyl Detoxification in Mammalian Schwann Cells. | 2017 Feb 24 |
1 |
| 12 |
28073699 | Activation of Nrf2 attenuates carbonyl stress induced by methylglyoxal in human neuroblastoma cells: Increase in GSH levels is a critical event for the detoxification mechanism. | 2017 Feb 5 |
1 |
| 13 |
28320998 | Design, Synthesis and Biological Evaluation of Potent Human Glyoxalase I Inhibitors. | 2017 May 1 |
4 |
| 14 |
28374736 | Biomimetic catalytic transformation of toxic α-oxoaldehydes to high-value chiral α-hydroxythioesters using artificial glyoxalase I. | 2017 Apr 4 |
1 |
| 15 |
28461715 | Glutathione in plants: biosynthesis and physiological role in environmental stress tolerance. | 2017 Apr |
1 |
| 16 |
27574401 | Novel glyoxalase-I inhibitors possessing a "zinc-binding feature" as potential anticancer agents. | 2016 |
1 |
| 17 |
24756473 | GSH protects against oxidative stress and toxicity in VL-17A cells exposed to high glucose. | 2015 Mar |
2 |
| 18 |
26320622 | Novel bivalent inhibitors with sub-nanomolar affinities towards human glyoxalase I. | 2015 Nov 1 |
2 |
| 19 |
26594764 | Inhibitory Effect of Isoflavones from Erythrina poeppigiana on the Growth of HL-60 Human Leukemia Cells through Inhibition of Glyoxalase I. | 2015 Sep |
1 |
| 20 |
24646266 | Measurement of glyoxalase activities. | 2014 Apr |
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| 21 |
24646274 | The temporal and spatial dynamics of glyoxalase I following excitoxicity and brain ischaemia. | 2014 Apr |
2 |
| 22 |
23360186 | Glyoxalase 1 enzyme activity in erythrocytes and Ala111Glu polymorphism in type 1-diabetes patients. | 2013 Mar |
3 |
| 23 |
22188542 | Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. | 2012 Apr 1 |
2 |
| 24 |
22247548 | Five decades with glutathione and the GSTome. | 2012 Feb 24 |
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| 25 |
22325990 | Methylglyoxal, advanced glycation end products and autism: is there a connection? | 2012 Apr |
2 |
| 26 |
22860189 | Potential of a γ-glutamyl-transpeptidase-stable glutathione analogue against amyloid-β toxicity. | 2012 Mar 21 |
4 |
| 27 |
23122816 | Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors. | 2012 Dec 15 |
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| 28 |
21310261 | Methylglyoxal metabolism in trypanosomes and leishmania. | 2011 May |
2 |
| 29 |
19493264 | Mode of cytotoxic action of nephrotoxic agents: oxidative stress and glutathione-dependent enzyme. | 2010 Jan |
2 |
| 30 |
20387042 | Metabolic engineering of glyoxalase pathway for enhancing stress tolerance in plants. | 2010 |
1 |
| 31 |
20454679 | Posttranslational modification of human glyoxalase 1 indicates redox-dependent regulation. | 2010 Apr 29 |
2 |
| 32 |
18533362 | Molecular enzymology of the glyoxalase system. | 2008 |
1 |
| 33 |
18946510 | Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity. | 2008 |
4 |
| 34 |
16781798 | Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers. | 2007 Jul |
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| 35 |
18409743 | [Crystalline silica can induce oxidative stress by inhibiting glyoxalase system in bronchial epithelial cells]. | 2007 Jul-Sep |
4 |
| 36 |
16430697 | Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme. | 2006 Feb |
1 |
| 37 |
16623434 | The role of the glyoxalase pathway in reducing mesothelial toxicity of glucose degradation products. | 2006 Mar-Apr |
1 |
| 38 |
16997560 | A metabolically stable tight-binding transition-state inhibitor of glyoxalase-I. | 2006 Dec 1 |
1 |
| 39 |
15686923 | Reversal of anticancer drug resistance by COTC based on intracellular glutathione and glyoxalase I. | 2005 Feb 15 |
4 |
| 40 |
15898727 | N-(2-hydroxypropyl)methacrylamide copolymers of a glutathione (GSH)-activated glyoxalase i inhibitor and DNA alkylating agent: synthesis, reaction kinetics with GSH, and in vitro antitumor activities. | 2005 May-Jun |
2 |
| 41 |
16037241 | Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease. | 2005 Jun |
1 |
| 42 |
14556652 | Investigation of metal binding and activation of Escherichia coli glyoxalase I: kinetic, thermodynamic and mutagenesis studies. | 2004 Jan 15 |
1 |
| 43 |
14577607 | Metabolism, not autoxidation, plays a role in alpha-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus. | 2003 Oct |
1 |
| 44 |
14641060 | Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation. | 2003 Dec |
1 |
| 45 |
12086016 | A possible regulatory role of glyoxalase I in cell viability of human prostate cancer. | 2002 May |
3 |
| 46 |
12405831 | Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. | 2002 Nov 6 |
3 |
| 47 |
12487151 | Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance. | 2002 Nov |
1 |
| 48 |
11139585 | A 33-kDa allergen from rice (Oryza sativa L. Japonica). cDNA cloning, expression, and identification as a novel glyoxalase I. | 2001 Apr 6 |
1 |
| 49 |
11306074 | Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications. | 2001 Jan 30 |
4 |
| 50 |
11368170 | Brief history of glyoxalase I and what we have learned about metal ion-dependent, enzyme-catalyzed isomerizations. | 2001 Mar 1 |
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