Glutathione

glyoxalase I ; Homo sapiens







84 Article(s)
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51 11459475 Active site structure and mechanism of human glyoxalase I-an ab initio theoretical study. 2001 Jul 25 1
52 10913283 Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation. 2000 Aug 1 1
53 11009366 Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor. 2000 Oct 5 1
54 11011147 Nitric oxide inactivates glyoxalase I in cooperation with glutathione. 2000 Oct 6
55 11212839 Characterization of glyoxalase I (E. coli)-inhibitor interactions by electrospray time-of-flight mass spectrometry and enzyme kinetic analysis. 2000 Jul 1
56 9679539 An evolutionary approach to the design of glutathione-linked enzymes. 1998 Apr 24 1
57 9679550 Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors. 1998 Apr 24 1
58 9108256 Diffusion-dependent kinetic properties of glyoxalase I and estimates of the steady-state concentrations of glyoxalase-pathway intermediates in glycolyzing erythrocytes. 1997 Mar 15 2
59 9218781 Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping. 1997 Jun 16 1
60 9359858 Mutagenesis of residue 157 in the active site of human glyoxalase I. 1997 Nov 15 2
61 8700107 Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. 1996 Jul 1
62 8942396 Negative association between erythrocyte reduced glutathione concentration and diabetic complications. 1996 Nov 1
63 7793109 Glyoxalase I activity in erythrocytes from severely malnourished children. 1995 Mar 5
64 8657641 [Role of glyoxalases and methylglyoxal in cell proliferation and differentiation]. 1995 1
65 7859825 Methylglyoxal concentration and glyoxalase activities in the human lens. 1994 Oct 1
66 8589803 S-fluorenylmethoxycarbonyl glutathione and diesters: inhibition of mammalian glyoxalase II. 1994-1995 1
67 7684374 Human glyoxalase I. cDNA cloning, expression, and sequence similarity to glyoxalase I from Pseudomonas putida. 1993 May 25 1
68 8489699 A simplified method for the purification of human red blood cell glyoxalase. I. Characteristics, immunoblotting, and inhibitor studies. 1993 Apr 1
69 1472100 Inhibition of proliferation of human leukaemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro. 1992 Dec 15 1
70 1627549 Isomerization of (R)- and (S)-glutathiolactaldehydes by glyoxalase I: the case for dichotomous stereochemical behavior in a single active site. 1992 Jul 7 1
71 2043110 Synthesis and initial characterization of gamma-L-glutamyl-L-thiothreonylglycine and gamma-L-glutamyl-L-allo-thiothreonylglycine as steric probes of the active site of glyoxalase I. 1991 May 31 1
72 2827734 Electron paramagnetic resonance study of the active site of copper-substituted human glyoxalase I. 1987 Oct 20 2
73 3947646 Inhibition of mammalian glyoxalase I (lactoylglutathione lyase) by N-acylated S-blocked glutathione derivatives as a probe for the role of the N-site of glutathione in glyoxalase I mechanism. 1986 Mar 7 4
74 3888271 Partial transition-state inhibitors of glyoxalase I from human erythrocytes, yeast and rat liver. 1985 May 20 3
75 3986216 The effect of glyoxalase I on the metabolism of 4,5-dioxovaleric acid. 1985 Apr 17 1
76 3994738 Red blood cell oxidative metabolism induced by hydroxypyruvaldehyde. 1985 Apr 15 2
77 6547959 NMR and computer modeling studies of the conformations of glutathione derivatives at the active site of glyoxalase I. 1984 Sep 25 2
78 6863314 Reversal of the reaction catalyzed by glyoxalase I. Calculation of the equilibrium constant for the enzymatic reaction. 1983 Jul 25 1
79 7138835 Fluorescence and nuclear relaxation enhancement studies of the binding of glutathione derivatives to manganese-reconstituted glyoxalase I from human erythrocytes. A model for the catalytic mechanism of the enzyme involving a hydrated metal ion. 1982 Sep 28 1
80 7024272 Deuterium isotope effects on the product partitioning of fluoromethylglyoxal by glyoxalase I. Proof of a proton transfer mechanism. 1981 Oct 10 1
81 6989637 A photoaffinity label derivative of glutathione and its inhibition of glyoxalase I. 1980 Feb 11 1
82 259500 Methylglyoxal production in human blood. 1978 1
83 690442 Concanavalin A increases glyoxalase enzyme activities in polymorphonuclear leukocytes and lymphocytes. 1978 Sep 2
84 4778269 gamma,delta-Dioxovalerate as a substrate for the glyoxalase enzyme system. 1973 Dec 1