Title : Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system.

Pub. Date : 2002 Nov 6

PMID : 12405831






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Its rate of ketonization is much too slow to be in the sequence required for the assay of MGS by coupling of the MG produced to glyoxalase I (Glx I): MG + glutathione (GSH) --> (S)-lactylglutathione (D-LG). Glutathione glyoxalase I Homo sapiens
2 Its rate of ketonization is much too slow to be in the sequence required for the assay of MGS by coupling of the MG produced to glyoxalase I (Glx I): MG + glutathione (GSH) --> (S)-lactylglutathione (D-LG). Glutathione glyoxalase I Homo sapiens
3 Instead, ketonization occurs by way of the hemithioacetal (HTA) formed between ePY and GSH, and could be either an enzymatic function of Glx I or occur nonenzymatically at an activated rate. Glutathione glyoxalase I Homo sapiens