| 1 |
35350668 | Dl-3-n-butylphthalide alleviates cognitive impairment in amyloid precursor protein/presenilin 1 transgenic mice by regulating the striatal-enriched protein tyrosine phosphatase/ERK/cAMP-response element-binding protein signaling pathway. | 2022 May |
1 |
| 2 |
29489891 | Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells. | 2018 |
2 |
| 3 |
28213521 | Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors. | 2017 Apr 7 |
2 |
| 4 |
28237515 | AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia. | 2017 May |
1 |
| 5 |
26577290 | ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss. | 2015 Nov 18 |
1 |
| 6 |
23318428 | Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase. | 2013 Nov 7 |
1 |
| 7 |
23456819 | Evidence that TMEM67 causes polycystic kidney disease through activation of JNK/ERK-dependent pathways. | 2013 Jul |
1 |
| 8 |
21943960 | Clozapine induction of ERK1/2 cell signalling via the EGF receptor in mouse prefrontal cortex and striatum is distinct from other antipsychotic drugs. | 2012 Sep |
1 |
| 9 |
22268811 | α(1A)-adrenergic receptor differentially regulates STAT3 phosphorylation through PKCϵ and PKCδ in myocytes. | 2012 Apr |
1 |
| 10 |
22683570 | Mitogen-activated protein kinase phosphatase 2, MKP-2, regulates early inflammation in acute lung injury. | 2012 Aug 1 |
1 |
| 11 |
21055728 | Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation. | 2011 Feb 1 |
1 |
| 12 |
21149602 | Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-γ1 phosphorylation. | 2011 Jan 15 |
1 |
| 13 |
22056552 | Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways. | 2011 Dec |
2 |
| 14 |
20348091 | Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. | 2010 May 21 |
1 |
| 15 |
20407013 | Activation by tyrosine phosphorylation as a prerequisite for protein kinase Cζ to mediate epidermal growth factor receptor signaling to ERK. | 2010 May |
2 |
| 16 |
20484411 | Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3. | 2010 Jul |
1 |
| 17 |
21220918 | TGF-β1 induces podocyte injury through Smad3-ERK-NF-κB pathway and Fyn-dependent TRPC6 phosphorylation. | 2010 |
1 |
| 18 |
18174162 | p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells. | 2008 Mar 7 |
1 |
| 19 |
16788692 | STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells. | 2006 Aug |
1 |
| 20 |
16982683 | ShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic development. | 2006 Dec |
2 |
| 21 |
17224080 | Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells. | 2006 Nov 29 |
2 |
| 22 |
15579467 | Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons. | 2005 Feb 18 |
1 |
| 23 |
15930121 | ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress. | 2005 Aug |
1 |
| 24 |
16103119 | Uncoupling ligand-dependent and -independent mechanisms for mitogen-activated protein kinase activation by the murine Ron receptor tyrosine kinase. | 2005 Oct 21 |
6 |
| 25 |
14764579 | Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke. | 2004 Apr 23 |
1 |
| 26 |
15174091 | PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation. | 2004 Aug |
1 |
| 27 |
15189452 | Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding. | 2004 Jun |
9 |
| 28 |
15344880 | Inhibition of phosphatidylinositol-3-kinase enhances insulin stimulation of insulin receptor substrate 1 tyrosine phosphorylation and extracellular signal-regulated kinases in mouse R- fibroblasts. | 2004 Feb |
2 |
| 29 |
15569927 | Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina. | 2004 Dec 7 |
1 |
| 30 |
12480085 | A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation. | 2003 Jan 15 |
1 |
| 31 |
12901876 | Raf1 plays a pivotal role in lipopolysaccharide-induced activation of dendritic cells. | 2003 Aug 22 |
2 |
| 32 |
11749069 | Differential response to Tat and FGF-2 of two novel clonal populations derived from murine Kaposi-like lesions developing in Tat transgenic mice. | 2002 Jan |
1 |
| 33 |
12270548 | Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes. | 2002 Nov 1 |
1 |
| 34 |
12402043 | Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. | 2002 Nov |
2 |
| 35 |
11457888 | Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. | 2001 Jul 16 |
1 |
| 36 |
10653972 | Fluid flow-induced tyrosine phosphorylation and participation of growth factor signaling pathway in osteoblast-like cells. | 2000 Jan |
1 |
| 37 |
10737896 | Tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin does not require extracellular signal-regulated kinase activation in Swiss 3T3 cells stimulated by bombesin or platelet-derived growth factor. | 2000 May |
2 |
| 38 |
10746631 | Domains of the insulin-like growth factor I receptor required for the activation of extracellular signal-regulated kinases. | 2000 Apr |
1 |
| 39 |
10820166 | Mitogen-activated protein kinase phosphorylation in kidneys of beta(s) sickle cell mice. | 2000 Jun |
1 |
| 40 |
10935641 | CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection. | 2000 Jul 27 |
1 |
| 41 |
10403397 | Actinomycin D as a novel SH2 domain ligand inhibits Shc/Grb2 interaction in B104-1-1 (neu*-transformed NIH3T3) and SAA (hEGFR-overexpressed NIH3T3) cells. | 1999 Jun 18 |
1 |
| 42 |
9712667 | Cerebellar brain-derived neurotrophic factor-TrkB defect associated with impairment of eyeblink conditioning in Stargazer mutant mice. | 1998 Sep 1 |
1 |
| 43 |
9774338 | Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration. | 1998 Oct 15 |
1 |
| 44 |
9822700 | Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation. | 1998 Nov 27 |
3 |
| 45 |
9009167 | Taxol induces tyrosine phosphorylation of Shc and its association with Grb2 in murine RAW 264.7 cells. | 1997 Jan 17 |
1 |
| 46 |
9075730 | Mechanism of mitogen-activated protein kinase activation by gonadotropin-releasing hormone in the pituitary of alphaT3-1 cell line: differential roles of calcium and protein kinase C. | 1997 Apr |
1 |
| 47 |
9148971 | Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells. | 1997 May 16 |
2 |
| 48 |
9361011 | Differentiation and transforming growth factor-beta receptor down-regulation by collagen-alpha2beta1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells. | 1997 Nov 14 |
3 |
| 49 |
10684111 | [Studies on cell signaling immunomodulated murine peritoneal suppressor macrophages: LPS and PMA mediate the activation of RAF-1, MAPK p44 and MAPK p42 and p38 MAPK]. | 1997 Mar |
1 |
| 50 |
8608974 | Tolerance to the anti-metastatic effect of lipopolysaccharide against liver metastasis in mice. | 1996 Mar 28 |
1 |