Title : Raf1 plays a pivotal role in lipopolysaccharide-induced activation of dendritic cells.

Pub. Date : 2003 Aug 22

PMID : 12901876






2 Functional Relationships(s)
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1 We demonstrated in DC2.4 dendritic cells that ERK regulates tyrosine phosphorylation of phosphatidyl-inositol-3-kinase (PI3-K) and the production of TNF-alpha. Tyrosine mitogen-activated protein kinase 1 Mus musculus
2 We also demonstrated that Raf1 is phosphorylated and involved in the production of TNF-alpha and tyrosine phosphorylation of PI3-K via ERK. Tyrosine mitogen-activated protein kinase 1 Mus musculus