Title : ShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic development.

Pub. Date : 2006 Dec

PMID : 16982683






2 Functional Relationships(s)
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1 We also identify two specific tyrosines on ShcA that promote ERK phosphorylation in vivo, and mice expressing ShcA with mutations of these tyrosines show impaired DN thymocyte development. Tyrosine mitogen-activated protein kinase 1 Mus musculus
2 We also identify two specific tyrosines on ShcA that promote ERK phosphorylation in vivo, and mice expressing ShcA with mutations of these tyrosines show impaired DN thymocyte development. Tyrosine mitogen-activated protein kinase 1 Mus musculus