Thioctic Acid

NFE2 like bZIP transcription factor 2 ; Homo sapiens







26 Article(s)
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1 35052616 Enantioselective Synthesis and Pharmacological Evaluation of Aza-CGP37157-Lipoic Acid Hybrids for the Treatment of Alzheimer's Disease. 2022 Jan 4 2
2 35563167 Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceuticals: A Practical Strategy for Preserving Bone Mass. 2022 Apr 26 1
3 33113440 Dietary alpha-lipoic acid supplementation improves spermatogenesis and semen quality via antioxidant and anti-apoptotic effects in aged breeder roosters. 2021 Jan 1 2
4 33671655 Amelioration of Metal-Induced Cellular Stress by α-Lipoic Acid and Dihydrolipoic Acid through Antioxidative Effects in PC12 Cells and Caco-2 Cells. 2021 Feb 22 3
5 34118221 Alpha lipoic acid priming enhances the hepatoprotective effect of adipose derived stem cells in CCl4 induced hepatic injury in-vitro. 2021 Sep 5 2
6 34211631 α-Lipoic Acid Targeting PDK1/NRF2 Axis Contributes to the Apoptosis Effect of Lung Cancer Cells. 2021 1
7 31693218 Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties. 2020 May 1
8 32061150 α-Lipoic acid protects against microcystin-LR induced hepatotoxicity through regeneration of glutathione via activation of Nrf2. 2020 Jul 7
9 30758914 Protective effects of α-lipoic acid on cultured human nasal fibroblasts exposed to urban particulate matter. 2019 Jun 3
10 31319135 Establishment of Nrf2-deficient HaCaT and immortalized primary human foreskin keratinocytes and characterization of their responses to ROS-induced cytotoxicity. 2019 Dec 5
11 31877176 α-Lipoic acid prevents against cisplatin cytotoxicity via activation of the NRF2/HO-1 antioxidant pathway. 2019 1
12 28349254 α-Lipoic acid prevents the intestinal epithelial monolayer damage under heat stress conditions: model experiments in Caco-2 cells. 2018 Jun 2
13 30096293 Alpha-lipoic acid, but not di-hydrolipoic acid, activates Nrf2 response in primary human umbilical-vein endothelial cells and protects against TNF-α induced endothelium dysfunction. 2018 Oct 1 3
14 30728952 Nrf2-Mediated Antioxidant Activity of the inner bark extracts obtained from Tabebuia rosea (Bertol) DC and Tabebuia chrysantha (JACQ) G. Nicholson. 2018 1
15 28262510 Regeneration of glutathione by α-lipoic acid via Nrf2/ARE signaling pathway alleviates cadmium-induced HepG2 cell toxicity. 2017 Apr 3
16 28366867 Cadmium and α-lipoic acid activate similar de novo synthesis and recycling pathways for glutathione balance. 2017 Jun 1
17 27292272 Immunomodulatory activities of alpha lipoic acid with a special focus on its efficacy in preventing miscarriage. 2016 Dec 1
18 27343752 α-Lipoic acid protects against the cytotoxicity and oxidative stress induced by cadmium in HepG2 cells through regeneration of glutathione by glutathione reductase via Nrf2/ARE signaling pathway. 2016 Jul 5
19 26299964 PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases. 2015 Sep 1 2
20 25123628 Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. 2014 Nov 1
21 23188707 Arsenic-mediated activation of the Nrf2-Keap1 antioxidant pathway. 2013 Feb 1
22 23573137 The protective effect of alpha-lipoic Acid in lipopolysaccharide-induced acute lung injury is mediated by heme oxygenase-1. 2013 2
23 22521877 Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response. 2012 Jun 1
24 21787596 Alpha-lipoic acid regulates heme oxygenase gene expression and nuclear Nrf2 activation as a mechanism of protection against arsenic exposure in HepG2 cells. 2010 Mar 4
25 18813798 Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells. 2008 Oct 1
26 16123320 Alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells. 2005 Oct 6