Pub. Date : 2020 Jul
PMID : 32061150
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | alpha-Lipoic acid protects against microcystin-LR induced hepatotoxicity through regeneration of glutathione via activation of Nrf2. | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
2 | Alpha-lipoic acid (alpha-LA) is a super antioxidant that can induce the synthesis of antioxidants, such as glutathione (GSH), by nuclear factor erythroid 2-related factor 2 (Nrf2). | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
3 | Alpha-lipoic acid (alpha-LA) is a super antioxidant that can induce the synthesis of antioxidants, such as glutathione (GSH), by nuclear factor erythroid 2-related factor 2 (Nrf2). | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
4 | Alpha-lipoic acid (alpha-LA) is a super antioxidant that can induce the synthesis of antioxidants, such as glutathione (GSH), by nuclear factor erythroid 2-related factor 2 (Nrf2). | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
5 | Alpha-lipoic acid (alpha-LA) is a super antioxidant that can induce the synthesis of antioxidants, such as glutathione (GSH), by nuclear factor erythroid 2-related factor 2 (Nrf2). | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
6 | alpha-LA can mediate GSH regeneration through the Nrf2 pathway under the action of glutathione reductase in MC-LR cell lines. | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
7 | Furthermore, the data also showed that alpha-LA-induced cytoprotection against MC-LR is associated with Nrf2 mediate pathway in vivo. | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |