Pub. Date : 2017 Apr
PMID : 28262510
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regeneration of glutathione by alpha-lipoic acid via Nrf2/ARE signaling pathway alleviates cadmium-induced HepG2 cell toxicity. | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | Addition of alpha-LA to cadmium-treated cells reactivated Nrf2 and regenerated GSH through elevating the Nrf2-downstream genes gamma-glutamate-cysteine ligase (gamma-GCL) and GR, both of which are key enzymes for GSH synthesis. | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | Addition of alpha-LA to cadmium-treated cells reactivated Nrf2 and regenerated GSH through elevating the Nrf2-downstream genes gamma-glutamate-cysteine ligase (gamma-GCL) and GR, both of which are key enzymes for GSH synthesis. | Thioctic Acid | NFE2 like bZIP transcription factor 2 | Homo sapiens |