Pub. Date : 2019 Sep
PMID : 30464227
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Importantly, a novel interaction between Vps26a and Nox4 linked to the activation of ERK1/2 depended highly on ROS levels during neurogenesis, which were strongly suppressed in differentiating Vps26a-/- ESCs. | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |
2 | Moreover, inhibition of phosphorylated ERK1/2 (pERK1/2) resulted in decreased ROS and Nox4 levels, indicating the mutual dependency between pERK1/2 and Nox4-derived ROS during neurogenesis. | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |
3 | Moreover, inhibition of phosphorylated ERK1/2 (pERK1/2) resulted in decreased ROS and Nox4 levels, indicating the mutual dependency between pERK1/2 and Nox4-derived ROS during neurogenesis. | Reactive Oxygen Species | mitogen-activated protein kinase 3 | Homo sapiens |