Pregnenolone Carbonitrile

nuclear receptor subfamily 1 group I member 2 ; Homo sapiens







13 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34447675 Interaction of Hepatitis B Virus X Protein with the Pregnane X Receptor Enhances the Synergistic Effects of Aflatoxin B1 and Hepatitis B Virus on Promoting Hepatocarcinogenesis. 2021 Aug 28 1
2 28624525 Regulation of hepatic abcb4 and cyp3a65 gene expression and multidrug/multixenobiotic resistance (MDR/MXR) functional activity in the model teleost, Danio rerio (zebrafish). 2017 Oct 3
3 24121122 Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio). 2013 Oct 15 1
4 22332017 MRP8/ABCC11 expression is regulated by dexamethasone in breast cancer cells and is associated to progesterone receptor status in breast tumors. 2011 3
5 19147857 Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR. 2009 Apr 1
6 17093002 The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. 2007 Feb 2
7 15367577 Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter. 2005 Feb 2
8 15180307 Trichostatin A, a histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in Hepa-I cells. 2004 Apr 1
9 15319343 Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues. 2004 Sep 2
10 15322232 Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier. 2004 Sep 2
11 12354121 Identification of residues in the PXR ligand binding domain critical for species specific and constitutive activation. 2002 Oct 2
12 11248085 The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. 2001 Mar 13 4
13 10462436 P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. 1999 Sep 1 2