Title : Effects of insulin and insulin-like growth factor 1 on osteoblast proliferation and differentiation: differential signalling via Akt and ERK.

Pub. Date : 2012 Jun

PMID : 22249904






2 Functional Relationships(s)
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1 The IGF-1-induced osteoblast proliferation was mediated via both MAPK and Akt pathways because the IGF-1-mediated cell proliferation was blocked by U0126, an MEK/MAPK inhibitor, or LY294002, a PI3-kinase inhibitor. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one insulin-like growth factor 1 Mus musculus
2 The IGF-1-induced osteoblast proliferation was mediated via both MAPK and Akt pathways because the IGF-1-mediated cell proliferation was blocked by U0126, an MEK/MAPK inhibitor, or LY294002, a PI3-kinase inhibitor. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one insulin-like growth factor 1 Mus musculus