Title : Possible involvement of phosphatidylinositol 3-kinase/Akt pathway in insulin-like growth factor-I-induced alkaline phosphatase activity in osteoblasts.

Pub. Date : 2005 May

PMID : 15971148






2 Functional Relationships(s)
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1 LY294002 and wortmannin, inhibitors of phosphatidylinositol 3-kinase, significantly suppressed the IGF-I-induced alkaline phosphatase activity. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one insulin-like growth factor 1 Mus musculus
2 The phosphorylation of Akt induced by IGF-I was markedly reduced by LY294002 and wortmannin. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one insulin-like growth factor 1 Mus musculus