| 1 |
35341775 | Metformin alleviates dexamethasone-induced apoptosis by regulating autophagy via AMPK/mTOR/p70S6K in osteoblasts. | 2022 Jun 1 |
4 |
| 2 |
32951587 | The Chemosensitizing Role of Metformin in Anti-Cancer Therapy. | 2021 |
1 |
| 3 |
34004440 | Metformin prevents BAFF activation of Erk1/2 from B-cell proliferation and survival by impeding mTOR-PTEN/Akt signaling pathway. | 2021 Jul |
1 |
| 4 |
34607979 | Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation. | 2021 Nov 1 |
1 |
| 5 |
31926250 | Inhibition of mTORC1/P70S6K pathway by Metformin synergistically sensitizes Acute Myeloid Leukemia to Ara-C. | 2020 Feb 15 |
3 |
| 6 |
30146703 | In vitro evaluation of effects of metformin on morphine and methadone tolerance through mammalian target of rapamycin signaling pathway. | 2019 Mar |
1 |
| 7 |
30720062 | Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. | 2019 Apr |
1 |
| 8 |
30753544 | Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects. | 2019 Jun 5 |
1 |
| 9 |
31028998 | Metformin inhibits the proliferation of rheumatoid arthritis fibroblast-like synoviocytes through IGF-IR/PI3K/AKT/m-TOR pathway. | 2019 Jul |
2 |
| 10 |
29472557 | Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. | 2018 Feb 22 |
1 |
| 11 |
29728793 | Metformin Protects Against Spinal Cord Injury by Regulating Autophagy via the mTOR Signaling Pathway. | 2018 May |
1 |
| 12 |
27128966 | Metformin induces degradation of cyclin D1 via AMPK/GSK3β axis in ovarian cancer. | 2017 Feb |
1 |
| 13 |
27856287 | The inhibition of spinal synaptic plasticity mediated by activation of AMP-activated protein kinase signaling alleviates the acute pain induced by oxaliplatin. | 2017 Feb |
2 |
| 14 |
27857021 | Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. | 2017 Jul |
1 |
| 15 |
28406985 | Metformin inhibited esophageal squamous cell carcinoma proliferation in vitro and in vivo and enhanced the anti-cancer effect of cisplatin. | 2017 |
2 |
| 16 |
29085506 | Role of metformin in inhibiting estrogen-induced proliferation and regulating ERα and ERβ expression in human endometrial cancer cells. | 2017 Oct |
2 |
| 17 |
26305116 | Metformin inhibits proliferation and proinflammatory cytokines of human keratinocytes in vitro via mTOR-signaling pathway. | 2016 Jul |
1 |
| 18 |
26669511 | Cation-selective transporters are critical to the AMPK-mediated antiproliferative effects of metformin in human breast cancer cells. | 2016 May 1 |
1 |
| 19 |
27135362 | Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State. | 2016 Mar 23 |
1 |
| 20 |
27246734 | Metformin preconditioning provide neuroprotection through enhancement of autophagy and suppression of inflammation and apoptosis after spinal cord injury. | 2016 Sep 2 |
2 |
| 21 |
27404348 | Metformin Elicits Antitumor Effects and Downregulates the Histone Methyltransferase Multiple Myeloma SET Domain (MMSET) in Prostate Cancer Cells. | 2016 Dec |
1 |
| 22 |
27916907 | Metformin Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition via PKM2 Relative-mTOR/p70s6k Signaling Pathway in Cervical Carcinoma Cells. | 2016 Nov 30 |
3 |
| 23 |
25817233 | AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells. | 2015 Jun 15 |
1 |
| 24 |
25921843 | Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial. | 2015 Jul |
2 |
| 25 |
26304716 | Radiosensitization of metformin in pancreatic cancer cells via abrogating the G2 checkpoint and inhibiting DNA damage repair. | 2015 Dec 1 |
1 |
| 26 |
26344902 | Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin. | 2015 Nov |
2 |
| 27 |
26391180 | Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling. | 2015 Sep 22 |
1 |
| 28 |
24505341 | Response of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combined. | 2014 |
1 |
| 29 |
24714080 | Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP. | 2014 Sep |
7 |
| 30 |
24750786 | Glioblastoma stem cells: a new target for metformin and arsenic trioxide. | 2014 Jan-Mar |
1 |
| 31 |
24858012 | Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells. | 2014 |
1 |
| 32 |
23449430 | Metformin impairs vascular endothelial recovery after stent placement in the setting of locally eluted mammalian target of rapamycin inhibitors via S6 kinase-dependent inhibition of cell proliferation. | 2013 Mar 5 |
1 |
| 33 |
23709654 | Treatment with metformin is associated with higher remission rate in diabetic patients with thyroid cancer. | 2013 Aug |
3 |
| 34 |
24335168 | Metformin inhibits esophagus cancer proliferation through upregulation of USP7. | 2013 |
1 |
| 35 |
22389381 | Metformin inhibits growth and decreases resistance to anoikis in medullary thyroid cancer cells. | 2012 Jun |
1 |
| 36 |
22500211 | Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells. | 2012 |
1 |
| 37 |
21168492 | Metformin promotes progesterone receptor expression via inhibition of mammalian target of rapamycin (mTOR) in endometrial cancer cells. | 2011 Sep |
2 |
| 38 |
21717584 | Metformin induces G1 cell cycle arrest and inhibits cell proliferation in nasopharyngeal carcinoma cells. | 2011 Aug |
1 |
| 39 |
20363874 | AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. | 2010 Jun |
1 |
| 40 |
18495226 | In vitro metformin anti-neoplastic activity in epithelial ovarian cancer. | 2008 Aug |
2 |
| 41 |
17698034 | Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes. | 2007 Oct 12 |
1 |