Title : Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects.

Pub. Date : 2019 Jun 5

PMID : 30753544






1 Functional Relationships(s)
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1 RESULTS: Metformin added to peripheral blood mononuclear cells from healthy volunteers enhanced in vitro cellular metabolism while inhibiting the mammalian target of rapamycin targets p70S6K and 4EBP1, with decreased cytokine production and cellular proliferation and increased phagocytosis activity. Metformin ribosomal protein S6 kinase B1 Homo sapiens