Phosphatidic Acids

mechanistic target of rapamycin kinase ; Homo sapiens







78 Article(s)
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1 34706625 The effects of phosphatidic acid on performance and body composition - a scoping review. 2022 Feb 4
2 33044904 BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation. 2021 Sep 1
3 33315072 Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner. 2021 Jan 4 2
4 33865870 Structural Basis of DEPTOR to Recognize Phosphatidic Acid Using its Tandem DEP Domains. 2021 Jun 25 2
5 34209150 Up-Regulation of Specific Bioactive Lipids in Celiac Disease. 2021 Jun 30 1
6 34345670 Optical Control of Phosphatidic Acid Signaling. 2021 Jul 28 5
7 32791090 Diacylglycerol kinase η regulates C2C12 myoblast proliferation through the mTOR signaling pathway. 2020 Oct 1
8 30764901 OLFM4 Inhibits Epithelial-Mesenchymal Transition and Metastatic Potential of Cervical Cancer Cells. 2019 Jul 12 4
9 31139627 Mechanical Stretch Induces mTOR Recruitment and Activation at the Phosphatidic Acid-Enriched Macropinosome in Muscle Cell. 2019 6
10 31563324 1,25-Dihydroxyvitamin D3 induces human myeloid cell differentiation via the mTOR signaling pathway. 2019 Nov 19 2
11 29136407 Phospholipase D inhibitors reduce human prostate cancer cell proliferation and colony formation. 2018 Jan 1
12 29703186 HPV-16 E7 expression up-regulates phospholipase D activity and promotes rapamycin resistance in a pRB-dependent manner. 2018 Apr 27 3
13 30054335 mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells. 2018 Sep 15 6
14 28092463 CCAAT/Enhancer-Binding Protein β Mediates the Killing of Toxoplasma gondii by Inducing Autophagy in Nonhematopoietic Cells. 2017 Mar 1
15 28184235 Phosphatidic acid: biosynthesis, pharmacokinetics, mechanisms of action and effect on strength and body composition in resistance-trained individuals. 2017 1
16 28223357 Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid. 2017 Apr 14 8
17 26787840 A Repertoire of MicroRNAs Regulates Cancer Cell Starvation by Targeting Phospholipase D in a Feedback Loop That Operates Maximally in Cancer Cells. 2016 Jan 19 2
18 26916116 The Enigma of Rapamycin Dosage. 2016 Mar 2
19 27274715 The effects of phosphatidic acid supplementation on strength, body composition, muscular endurance, power, agility, and vertical jump in resistance trained men. 2016 4
20 27891502 Diacylglycerol Kinases in T Cell Tolerance and Effector Function. 2016 1
21 25632961 Reciprocal regulation of AMP-activated protein kinase and phospholipase D. 2015 Mar 13 4
22 25936805 Rapid mitogenic regulation of the mTORC1 inhibitor, DEPTOR, by phosphatidic acid. 2015 May 7 2
23 26323019 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) enhances the efficacy of rapamycin in human cancer cells. 2015 2
24 26566242 The mechanistic and ergogenic effects of phosphatidic acid in skeletal muscle. 2015 Dec 5
25 24162376 The mechanical activation of mTOR signaling: an emerging role for late endosome/lysosomal targeting. 2014 Feb 2
26 24302719 The role of diacylglycerol kinase ζ and phosphatidic acid in the mechanical activation of mammalian target of rapamycin (mTOR) signaling and skeletal muscle hypertrophy. 2014 Jan 17 12
27 24708409 Diacylglycerol kinase as a possible therapeutic target for neuronal diseases. 2014 Apr 7 1
28 24990952 Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR). 2014 Aug 15 6
29 25137020 Phorbol ester stimulates ethanolamine release from the metastatic basal prostate cancer cell line PC3 but not from prostate epithelial cell lines LNCaP and P4E6. 2014 Oct 14 1
30 23208958 A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells. 2013 Feb 2
31 23426360 Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association. 2013 Apr 5 1
32 23507202 Phosphatidic acid and lipid-sensing by mTOR. 2013 Jun 2
33 23767959 Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes. 2013 Sep 1 5
34 23817226 Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. 2013 4
35 24009738 The role of phospholipase D in modulating the MTOR signaling pathway in polycystic kidney disease. 2013 4
36 24068326 Distinct amino acid-sensing mTOR pathways regulate skeletal myogenesis. 2013 Dec 1
37 24205284 Lysophosphatidic acid acyltransferase beta regulates mTOR signaling. 2013 2
38 22187071 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer. 2012 Dec 2
39 22472346 Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes. 2012 Jun 10 1
40 22952117 Diabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death. 2012 Oct 19 7
41 23035701 Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men. 2012 Oct 5 4
42 21510936 Modulation of oxidative stress and tau phosphorylation by the mTOR activator phosphatidic acid in SH-SY5Y cells. 2011 Jun 23 2
43 21622984 Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1). 2011 Jul 22 1
44 21737445 Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect. 2011 Aug 26 3
45 20372065 Reduced mortality and moderate alcohol consumption: the phospholipase D-mTOR connection. 2010 Apr 1 3
46 20427710 Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway. 2010 Aug 4
47 20438709 Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway. 2010 May 28 4
48 20623096 New concepts in phospholipase D signaling in inflammation and cancer. 2010 Jul 7 5
49 21137347 [Antiproliferation of cardamonin associated with mRNA expression of mTOR, Raptor and Rictor]. 2010 Sep 1
50 21203441 Translational up-regulation and high-level protein expression from plasmid vectors by mTOR activation via different pathways in PC3 and 293T cells. 2010 Dec 28 4