| 1 |
34719826 | Loperamide potentiates doxorubicin sensitivity in triple-negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl-2: In vitro and molecular docking study. | 2022 Jan |
1 |
| 2 |
35053325 | Transient Exposure of Endothelial Cells to Doxorubicin Leads to Long-Lasting Vascular Endothelial Growth Factor Receptor 2 Downregulation. | 2022 Jan 8 |
1 |
| 3 |
35134463 | SIRT4 Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the AKT/mTOR/Autophagy Pathway. | 2022 Mar 15 |
3 |
| 4 |
35311115 | Targeting the lncRNA DUXAP8/miR-29a/PIK3CA Network Restores Doxorubicin Chemosensitivity via PI3K-AKT-mTOR Signaling and Synergizes With Inotuzumab Ozogamicin in Chemotherapy-Resistant B-Cell Acute Lymphoblastic Leukemia. | 2022 |
6 |
| 5 |
35430482 | Spinacetin alleviates doxorubicin-induced cardiotoxicity by initiating protective autophagy through SIRT3/AMPK/mTOR pathways. | 2022 Jul |
2 |
| 6 |
33115283 | Combination treatment strategies with a focus on rosiglitazone and adriamycin for insulin resistant liver cancer. | 2021 Mar |
1 |
| 7 |
33799790 | Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells. | 2021 Mar 11 |
2 |
| 8 |
34223631 | Dual PI3K/mTOR inhibitor NVP‑BEZ235 decreases the proliferation of doxorubicin‑resistant K562 cells. | 2021 Apr |
3 |
| 9 |
34230123 | Combination of CDK4/6 and mTOR Inhibitors Suppressed Doxorubicin-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model: A Translatable Strategy for Recalcitrant Disease. | 2021 Jul |
1 |
| 10 |
34357784 | Retraction of: miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-I3K/AKT/mTOR Signaling Pathway (doi: 10.1089/cbr.2017.2306). | 2021 Sep |
1 |
| 11 |
34750375 | TCP1 increases drug resistance in acute myeloid leukemia by suppressing autophagy via activating AKT/mTOR signaling. | 2021 Nov 8 |
1 |
| 12 |
34778055 | HMGB1 Promotes Resistance to Doxorubicin in Human Hepatocellular Carcinoma Cells by Inducing Autophagy via the AMPK/mTOR Signaling Pathway. | 2021 |
3 |
| 13 |
34869595 | Ad-Apoptin-hTERTp-E1a Regulates Autophagy Through the AMPK-mTOR-eIF4F Signaling Axis to Reduce Drug Resistance of MCF-7/ADR Cells. | 2021 |
3 |
| 14 |
31707337 | Magnoflorine improves sensitivity to doxorubicin (DOX) of breast cancer cells via inducing apoptosis and autophagy through AKT/mTOR and p38 signaling pathways. | 2020 Jan |
3 |
| 15 |
31899608 | MicroRNA-221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling. | 2020 Feb |
2 |
| 16 |
32016465 | Low‑intensity ultrasound enhances the antitumor effects of doxorubicin on hepatocellular carcinoma cells through the ROS‑miR‑21‑PTEN axis. | 2020 Mar |
4 |
| 17 |
32061787 | A dual PI3 kinase/mTOR inhibitor BEZ235 reverses doxorubicin resistance in ABCB1 overexpressing ovarian and pancreatic cancer cell lines. | 2020 Jun |
1 |
| 18 |
32184626 | Berberine Reverses Doxorubicin Resistance by Inhibiting Autophagy Through the PTEN/Akt/mTOR Signaling Pathway in Breast Cancer. | 2020 |
1 |
| 19 |
32742395 | Elevated estrogen receptor β expression in triple negative breast cancer cells is associated with sensitivity to doxorubicin by inhibiting the PI3K/AKT/mTOR signaling pathway. | 2020 Aug |
3 |
| 20 |
32750329 | Resolvin E1 protects against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress, autophagy and apoptosis by targeting AKT/mTOR signaling. | 2020 Oct |
3 |
| 21 |
32968631 | Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner. | 2020 Aug |
2 |
| 22 |
32983965 | GZ17-6.02 and Doxorubicin Interact to Kill Sarcoma Cells via Autophagy and Death Receptor Signaling. | 2020 |
1 |
| 23 |
33218396 | Inhibitory effects of everolimus in combination with paclitaxel on adriamycin-resistant breast cancer cell line MDA-MB-231. | 2020 Nov |
1 |
| 24 |
33344906 | Empagliflozin and Doxorubicin Synergistically Inhibit the Survival of Triple-Negative Breast Cancer Cells via Interfering with the mTOR Pathway and Inhibition of Calmodulin: In Vitro and Molecular Docking Studies. | 2020 Dec 11 |
1 |
| 25 |
30627877 | Inhibition of AKT signalling by benzoxazine derivative LTUR6 through the modulation of downstream kinases. | 2019 Aug |
1 |
| 26 |
30720129 | Long non‑coding RNA linc00239 promotes malignant behaviors and chemoresistance against doxorubicin partially via activation of the PI3K/Akt/mTOR pathway in acute myeloid leukaemia cells. | 2019 Apr |
1 |
| 27 |
31281438 | Knockdown of lncRNA-HOTAIR downregulates the drug-resistance of breast cancer cells to doxorubicin via the PI3K/AKT/mTOR signaling pathway. | 2019 Jul |
5 |
| 28 |
31404320 | Rapamycin enhanced the antitumor effects of doxorubicin in myelogenous leukemia K562 cells by downregulating the mTOR/p70S6K pathway. | 2019 Sep |
4 |
| 29 |
31848319 | Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin. | 2019 Dec 17 |
1 |
| 30 |
32130607 | Resistance of THP-1 Leukemia Cells Infected with Cytomegalovirus to Anti-tumor Antibiotic Doxorubicin and Restoration of the Sensitivity by Inhibitors of the PI3K/AKT/mTOR Molecular Pathway. | 2019 Nov |
1 |
| 31 |
28797827 | Interaction between mTOR pathway inhibition and autophagy induction attenuates adriamycin-induced vascular smooth muscle cell senescence through decreased expressions of p53/p21/p16. | 2018 Aug |
4 |
| 32 |
29307829 | Blockage of cytosolic phospholipase A2 alpha sensitizes aggressive breast cancer to doxorubicin through suppressing ERK and mTOR kinases. | 2018 Jan 29 |
1 |
| 33 |
29412697 | miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-PI3K/AKT/mTOR Signaling Pathway. | 2018 Feb |
2 |
| 34 |
29710492 | Shufeng Jiedu Capsule and its active ingredients induce apoptosis, inhibit migration and invasion, and enhances doxorubicin therapeutic efficacy in hepatocellular carcinoma. | 2018 Mar |
1 |
| 35 |
29959912 | SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling. | 2018 Sep 15 |
1 |
| 36 |
30151071 | Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin-Induced Apoptosis Mediated through the Akt-mTOR Pathway in Soleus Muscle. | 2018 |
4 |
| 37 |
30181466 | DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways. | 2018 Sep 4 |
1 |
| 38 |
30282915 | Prodigiosin-Emerged PI3K/Beclin-1-Independent Pathway Elicits Autophagic Cell Death in Doxorubicin-Sensitive and -Resistant Lung Cancer. | 2018 Oct 3 |
1 |
| 39 |
30351976 | Protective effect of irbesartan against doxorubicin-induced nephrotoxicity in rats: implication of AMPK, PI3K/Akt, and mTOR signaling pathways. | 2018 Dec |
2 |
| 40 |
27845214 | Fabrication of self-assembled chitosan-dispersed LDL nanoparticles for drug delivery with a one-step green method. | 2017 Jan 30 |
1 |
| 41 |
28052008 | Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. | 2017 Jan 31 |
1 |
| 42 |
28108310 | Autophagic dysregulation in doxorubicin cardiomyopathy. | 2017 Mar |
1 |
| 43 |
28401013 | Resistin confers resistance to doxorubicin-induced apoptosis in human breast cancer cells through autophagy induction. | 2017 |
1 |
| 44 |
28542038 | Hypoxia as a target for drug combination therapy of liver cancer. | 2017 Aug |
1 |
| 45 |
28600513 | TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway. | 2017 Jun 9 |
1 |
| 46 |
28603284 | Transcription factor EB is involved in autophagy-mediated chemoresistance to doxorubicin in human cancer cells. | 2017 Sep |
1 |
| 47 |
28609310 | Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin. | 2017 Sep |
2 |
| 48 |
28767526 | Exercise Protects Skeletal Muscle during Chronic Doxorubicin Administration. | 2017 Dec |
3 |
| 49 |
28937626 | Aspalathin Reverts Doxorubicin-Induced Cardiotoxicity through Increased Autophagy and Decreased Expression of p53/mTOR/p62 Signaling. | 2017 Sep 22 |
2 |
| 50 |
29029490 | 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. | 2017 Sep 12 |
4 |