Pub. Date : 2017 Sep 22
PMID : 28937626
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aspalathin Reverts Doxorubicin-Induced Cardiotoxicity through Increased Autophagy and Decreased Expression of p53/mTOR/p62 Signaling. | Doxorubicin | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | Increasing evidence indicates that tumour protein p53 (p53), adenosine monophosphate-activated protein kinase (AMPK), nucleoporin p62 (p62), and the mammalian target of rapamycin (mTOR) are critical mediators of Dox-induced apoptosis, and subsequent dysregulation of autophagy. | Doxorubicin | mechanistic target of rapamycin kinase | Homo sapiens |