Serine

mitogen-activated protein kinase 8 ; Homo sapiens







174 Article(s)
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51 22750292 Paxillin is the target of c-Jun N-terminal kinase in Schwann cells and regulates migration. 2012 Nov 1
52 22771387 TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner. 2012 Nov 1
53 22865050 Paxillin phosphorylation by JNK and p38 is required for NFAT activation. 2012 Aug 1
54 22924711 Acetate reduces microglia inflammatory signaling in vitro. 2012 Nov 1
55 23056407 Evolutionary conserved role of c-Jun-N-terminal kinase in CO2-induced epithelial dysfunction. 2012 2
56 21030692 JNK regulates binding of alpha-catenin to adherens junctions and cell-cell adhesion. 2011 Feb 2
57 21123173 Deactivation of STAT6 through serine 707 phosphorylation by JNK. 2011 Feb 4 4
58 21465527 PTH regulates myleoid ELF-1-like factor (MEF)-induced MAB-21-like-1 (MAB21L1) expression through the JNK1 pathway. 2011 Aug 1
59 21478152 Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways. 2011 May 27 4
60 21502402 Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness. 2011 Jun 1 2
61 21540183 Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity. 2011 Jun 24 2
62 21807946 SCFβ(TrCP) mediates stress-activated MAPK-induced Cdc25B degradation. 2011 Aug 15 1
63 21840417 Novel participation of transglutaminase-2 through c-Jun N-terminal kinase activation in sphingosylphosphorylcholine-induced keratin reorganization of PANC-1 cells. 2011 Dec 3
64 21900690 Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK. 2011 Dec 2
65 20028971 c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82. 2010 Feb 26 3
66 20219981 Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells. 2010 May 1
67 20220133 JNK-mediated phosphorylation of Cdc25C regulates cell cycle entry and G(2)/M DNA damage checkpoint. 2010 May 7 1
68 20452983 The PEA-15 protein regulates autophagy via activation of JNK. 2010 Jul 9 2
69 20510162 Toll-like receptor 4-mediated c-Jun N-terminal kinase activation induces gp96 cell surface expression via AIMP1 phosphorylation. 2010 Jun 18 1
70 20541543 Inhibitory effect on protein kinase Ctheta by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes. 2010 Sep 10 1
71 20630875 c-Jun N-terminal kinase phosphorylation of stathmin confers protection against cellular stress. 2010 Sep 10 4
72 20814545 TLR4 and Insulin Resistance. 2010 1
73 19054758 Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody. 2009 Apr 2
74 19153595 The TAK1-JNK cascade is required for IRF3 function in the innate immune response. 2009 Apr 2
75 19220809 14-3-3 ligand prevents nuclear import of c-ABL protein in chronic myeloid leukemia. 2009 Jun 1
76 19567513 c-Jun N-terminal kinase 1/2 activation by tumor necrosis factor-alpha induces insulin resistance in human visceral but not subcutaneous adipocytes: reversal by liver X receptor agonists. 2009 Sep 2
77 19625654 Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages. 2009 Aug 15 1
78 19667122 JNK phosphorylates beta-catenin and regulates adherens junctions. 2009 Nov 1
79 19778898 JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2. 2009 Nov 20 1
80 19789335 Mutant p53 disrupts the stress MAPK activation circuit induced by ASK1-dependent stabilization of Daxx. 2009 Oct 1 1
81 17602798 3D-QSAR and docking studies of aminopyridine carboxamide inhibitors of c-Jun N-terminal kinase-1. 2008 Mar 2
82 17647275 Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells. 2008 Feb 15 1
83 17933493 Sequential activation of protein kinase C delta and JNK is required for interferon-alpha-induced expression of IFIT4. 2008 Jan 1
84 18172084 Role of JNK-dependent serine phosphorylation of paxillin in migration of corneal epithelial cells during wound closure. 2008 Jan 2
85 18337589 Cross talk of signaling pathways in the regulation of the glucocorticoid receptor function. 2008 Jun 1
86 18375956 Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway. 2008 Jun 7
87 18431843 The c-Jun N-terminal kinase JNK functions upstream of Aurora B to promote entry into mitosis. 2008 Feb 15 1
88 18553930 Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity. 2008 Jul 8 2
89 18667537 Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 Oct 1
90 18713649 JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin. 2008 Nov 2
91 18813807 Rac1 mediates phorbol 12-myristate 13-acetate-induced migration of glioblastoma cells via paxillin. 2008 Oct 1
92 18822310 Arsenic trioxide phosphorylates c-Fos to transactivate p21(WAF1/CIP1) expression. 2008 Dec 1 1
93 17023523 Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation. 2007 Jan 2
94 17279354 C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport. 2007 Apr 4
95 17389591 RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. 2007 May 18 2
96 17440071 P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation. 2007 Apr 15 1
97 17505626 [Insulin and angiotensin II signaling pathways cross-talk: implications with the association between diabetes mellitus, arterial hypertension and cardiovascular disease]. 2007 Mar 1
98 17568190 Pin1 in neuronal apoptosis. 2007 Jun 1 1
99 17568772 Negative regulation of SEK1 signaling by serum- and glucocorticoid-inducible protein kinase 1. 2007 Jul 11 1
100 17637928 Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway. 2007 Jul 1