Title : Sequential activation of protein kinase C delta and JNK is required for interferon-alpha-induced expression of IFIT4.

Pub. Date : 2008 Jan

PMID : 17933493






1 Functional Relationships(s)
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1 The inhibition of JNK activity by its specific inhibitor or its dominant negative mutant suppressed both IFIT4 expression and serine phosphorylation of STAT1 but not the activation of PKCdelta, while inhibition of PKCdelta suppressed activation of IFIT4, STAT1, and JNK. Serine mitogen-activated protein kinase 8 Homo sapiens