Title : Acetate reduces microglia inflammatory signaling in vitro.

Pub. Date : 2012 Nov

PMID : 22924711






1 Functional Relationships(s)
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1 LPS increased p38 MAPK and JNK phosphorylation at 4 and 2-4 h, respectively, whereas treatment reduced p38 MAPK and JNK phosphorylation only at 2 h. In addition, treatment reversed the LPS-induced elevation of NF-kappaB p65 protein and phosphorylation at serine 468 and induced acetylation at lysine 310. Serine mitogen-activated protein kinase 8 Homo sapiens