Title : Impaired platelet function in a patient with P2Y12 deficiency caused by a mutation in the translation initiation codon.

Pub. Date : 2005 Oct

PMID : 16194207






1 Functional Relationships(s)
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1 Our data suggest that secretion of endogenous ADP and subsequent P2Y12-mediated signaling are critical for platelet aggregation, platelet spreading, and as a consequence, for stabilization of thrombus. Adenosine Diphosphate purinergic receptor P2Y12 Homo sapiens