Methotrexate

solute carrier organic anion transporter family member 1B1 ; Homo sapiens







40 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34423897 SLCO1B1 *15 allele is associated with methotrexate-induced nausea in pediatric patients with inflammatory bowel disease. 2022 Jan 5
2 34726639 Association between SLCO1B1 polymorphism and methotrexate-induced hepatotoxicity: a systematic review and meta-analysis. 2022 Jan 1 6
3 35138194 Unexpected severe hepatic and skin toxicities during high dose methotrexate course for osteosarcoma. 2022 Feb 9 1
4 32961024 Effect of SLCO1B1 Polymorphisms on High-Dose Methotrexate Clearance in Children and Young Adults With Leukemia and Lymphoblastic Lymphoma. 2021 Jan 4
5 33025831 SLCO1B1 variants as predictors of methotrexate-related toxicity in children with juvenile idiopathic arthritis. 2021 May 6
6 33501733 Genetic factors involved in delayed methotrexate elimination in children with acute lymphoblastic leukemia. 2021 May 2
7 33565324 ABCB1 and SLCO1B1 gene polymorphisms predict methotrexate-resistant for low-risk gestational trophoblastic neoplasia. 2021 Mar 1
8 34121338 Toward pharmacogenetic SLCO1B1-guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model. 2021 Nov 3
9 34200242 Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies. 2021 Jun 7 1
10 32407928 Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms. 2020 Jul 15 1
11 33361876 Delayed Methotrexate Elimination after Administration of a Medium Dose of Methotrexate in a Patient with Genetic Variants Associated with Methotrexate Clearance. 2020 Dec 1
12 30677213 Delayed methotrexate clearance in patients with acute lymphoblastic leukemia concurrently receiving dasatinib. 2019 May 3
13 30782852 Organic Anion Transporting Polypeptides: Emerging Roles in Cancer Pharmacology. 2019 May 1
14 30931851 Methotrexate Disposition in Pediatric Patients with Acute Lymphoblastic Leukemia: What Have We Learnt From the Genetic Variants of Drug Transporters. 2019 1
15 31181069 Influence of genetic factors on long-term treatment related neurocognitive complications, and on anxiety and depression in survivors of childhood acute lymphoblastic leukemia: The Petale study. 2019 1
16 31267867 Influence of the OATP Polymorphism on the Population Pharmacokinetics of Methotrexate in Chinese Patients. 2019 5
17 31292326 Polymorphism in Organic Anion-Transporting Polypeptide Gene Related to Methotrexate Response in Rheumatoid Arthritis Treatment. 2019 1
18 31777781 Association of SLCO1B1 *14 Allele with Poor Response to Methotrexate in Juvenile Idiopathic Arthritis Patients. 2019 Mar 8
19 29285751 Endogenous Metabolites-Mediated Communication Between OAT1/OAT3 and OATP1B1 May Explain the Association Between SLCO1B1 SNPs and Methotrexate Toxicity. 2018 Oct 3
20 29683944 SLCO1B1 Polymorphisms are Associated With Drug Intolerance in Childhood Leukemia Maintenance Therapy. 2018 Jul 2
21 28391009 The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance Treatment. 2017 Apr 2
22 29095107 SLCO1B1 rs4149056 genetic polymorphism predicting methotrexate toxicity in Chinese patients with non-Hodgkin lymphoma. 2017 Nov 3
23 26131212 Association of SLCO1B1 gene polymorphisms with toxicity response of high dose methotrexate chemotherapy in childhood acute lymphoblastic leukemia. 2015 5
24 26474710 Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo. 2015 Dec 7 2
25 25007187 Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. 2014 Aug 2
26 25098908 Influence of the folate pathway and transporter polymorphisms on methotrexate treatment outcome in osteosarcoma. 2014 Oct 3
27 25124723 SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients. 2014 Nov 3
28 25130190 Impact of SLCO1B1 521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high-dose methotrexate. 2014 Dec 4
29 25309579 A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required. 2014 1
30 23222202 Polymorphisms in the methotrexate transport pathway: a new tool for MTX plasma level prediction in pediatric acute lymphoblastic leukemia. 2013 Feb 2
31 23233662 Genome-wide study of methotrexate clearance replicates SLCO1B1. 2013 Feb 7 3
32 23243220 Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice. 2013 Feb 15 3
33 23652803 Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia. 2013 Jun 27 2
34 22147369 Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition. 2012 Jan 3
35 22838946 Genetic variants in the human SLCO1B1 gene and individual variations in methotrexate clearance. 2012 Jul 1
36 21245207 Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake. 2011 Mar 2
37 21387541 Polymorphisms of the SLCO1B1 gene predict methotrexate-related toxicity in childhood acute lymphoblastic leukemia. 2011 Oct 4
38 22041697 [Genetic polymorphisms of SLCO1B1 for drug pharmacokinetics and its clinical implications]. 2011 3
39 19022939 Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1). 2009 Feb 9
40 19901119 Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. 2009 Dec 10 2