Pub. Date : 2014 Oct
PMID : 25098908
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Polymorphic SLCO1B1 rs4149056 and rs11045879 alleles were associated with significantly higher serum methotrexate area under the curve (P=0.001 and 0.011, respectively). | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | CONCLUSION: We have shown that SLCO1B1 polymorphisms influence methotrexate disposition and survival in methotrexate-treated osteosarcoma patients and therefore might serve as pharmacogenetic markers of treatment outcome. | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 3 | CONCLUSION: We have shown that SLCO1B1 polymorphisms influence methotrexate disposition and survival in methotrexate-treated osteosarcoma patients and therefore might serve as pharmacogenetic markers of treatment outcome. | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |