Pub. Date : 2015
PMID : 26131212
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: We found there was a statistically significant association between MTX plasma concentration and the SLCO1B1 rs11045879 CC genotype (P<0.05). | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | Association of SLCO1B1 gene polymorphisms with toxicity response of high dose methotrexate chemotherapy in childhood acute lymphoblastic leukemia. | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 3 | OBJECTIVE: The present study aims to investigate the correlation of polymorphisms of SLCO1B1 gene with the toxicity during therapy with the high-dose methotrexate (MTX) chemotherapy in childhood acute lymphoblastic leukemia. | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 4 | OBJECTIVE: The present study aims to investigate the correlation of polymorphisms of SLCO1B1 gene with the toxicity during therapy with the high-dose methotrexate (MTX) chemotherapy in childhood acute lymphoblastic leukemia. | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 5 | METHODS: We analyzed 2 polymorphisms (rs4149081 and rs11045897) in SLCO1B1 gene in 280 Chinese pediatric B-ALL patients, using MTX plasma concentration as an objective and quantifiable marker of toxicity. | Methotrexate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |