Title : Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer.

Pub. Date : 2017 Aug

PMID : 28789432






1 Functional Relationships(s)
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1 In addition, luteolin combined with LY294002 markedly increased the Bax/Bcl-2 ratio, while when combined with U0126, luteolin had less effects on the Bax/Bcl-2 ratio compared with luteolin treatment alone, suggesting that both the MAPK and PI3K signaling pathways are involved in the apoptosis induced by luteolin. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one BCL2 apoptosis regulator Homo sapiens