| 1 |
35079096 | Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule-1 (ICAM-1). | 2022 Jan 25 |
1 |
| 2 |
32657143 | Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line. | 2021 |
1 |
| 3 |
33268288 | Metformin decreased myocardial fibrosis and apoptosis in hyperhomocysteinemia -induced cardiac hypertrophy. | 2021 Jan |
1 |
| 4 |
33652909 | Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis. | 2021 Feb 26 |
1 |
| 5 |
33752282 | Hypoxia-Induced Suppression of Antiapoptotic Bcl-2 Expression in Human Bladder Tumor Cells Is Regulated by Caveolin-1-Dependent Adenosine Monophosphate-Activated Protein Kinase Activity. | 2021 Jun |
1 |
| 6 |
34078517 | Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism. | 2021 Jun 1 |
3 |
| 7 |
34573418 | Metformin Triggers Apoptosis and Induction of the G0/G1 Switch 2 Gene in Macrophages. | 2021 Sep 17 |
1 |
| 8 |
34607979 | Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation. | 2021 Nov 1 |
1 |
| 9 |
32248666 | Metformin revert insulin-induced oxaliplatin resistance by activating mitochondrial apoptosis pathway in human colon cancer HCT116 cells. | 2020 Jun |
1 |
| 10 |
32258099 | Metformin's Effects on Apoptosis of Esophageal Carcinoma Cells and Normal Esophageal Epithelial Cells: An In Vitro Comparative Study. | 2020 |
2 |
| 11 |
32495867 | Metformin reduces pancreatic cancer cell proliferation and increases apoptosis through MTOR signaling pathway and its dose-effect relationship. | 2020 May |
1 |
| 12 |
32792943 | Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells. | 2020 |
1 |
| 13 |
30625181 | Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells. | 2019 |
2 |
| 14 |
30720062 | Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. | 2019 Apr |
1 |
| 15 |
30936596 | Induction of Apoptosis by a Combination of 2-Deoxyglucose and Metformin in Esophageal Squamous Cell Carcinoma by Targeting Cancer Cell Metabolism. | 2019 Mar |
3 |
| 16 |
31014173 | Fibroblasts rescue oral squamous cancer cell from metformin-induced apoptosis via alleviating metabolic disbalance and inhibiting AMPK pathway. | 2019 May |
1 |
| 17 |
31173255 | Effect of metformin on cell proliferation, apoptosis, migration and invasion in A172 glioma cells and its mechanisms. | 2019 Aug |
1 |
| 18 |
31220411 | Metformin inhibits Aβ25-35 -induced apoptotic cell death in SH-SY5Y cells. | 2019 Nov |
1 |
| 19 |
29399562 | Antidiabetic Drug Metformin Protects Neuronal Cells against Quinolinic Acid-Induced Excitotoxicity by Decreasing Intracellular Calcium. | 2018 Jan |
1 |
| 20 |
29765528 | Metabolic changes associated with metformin potentiates Bcl-2 inhibitor, Venetoclax, and CDK9 inhibitor, BAY1143572 and reduces viability of lymphoma cells. | 2018 Apr 20 |
1 |
| 21 |
30088260 | Metformin inhibits human breast cancer cell growth by promoting apoptosis via a ROS-independent pathway involving mitochondrial dysfunction: pivotal role of superoxide dismutase (SOD). | 2018 Dec |
1 |
| 22 |
28345832 | Metformin Inhibits Migration and Invasion of Cholangiocarcinoma Cells | 2017 Feb 1 |
1 |
| 23 |
28378944 | Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells. | 2017 Jun |
1 |
| 24 |
28927780 | Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells. | 2017 Sep |
1 |
| 25 |
28964970 | Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation. | 2017 Dec |
1 |
| 26 |
29085821 | Screening Novel Molecular Targets of Metformin in Breast Cancer by Proteomic Approach. | 2017 |
1 |
| 27 |
29344202 | Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2. | 2017 Dec |
1 |
| 28 |
27168791 | Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro. | 2016 May |
3 |
| 29 |
27246734 | Metformin preconditioning provide neuroprotection through enhancement of autophagy and suppression of inflammation and apoptosis after spinal cord injury. | 2016 Sep 2 |
1 |
| 30 |
27391065 | Metformin as a new anti-cancer drug in adrenocortical carcinoma. | 2016 Aug 2 |
1 |
| 31 |
27517917 | The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer. | 2016 Aug 10 |
1 |
| 32 |
25492486 | Metformin sensitizes hepatocellular carcinoma to arsenic trioxide-induced apoptosis by downregulating Bcl2 expression. | 2015 Apr |
3 |
| 33 |
25495168 | The effect of Metformin on endometrial tumor-regulatory genes and systemic metabolic parameters in polycystic ovarian syndrome--a proof-of-concept study. | 2015 Apr |
1 |
| 34 |
25542900 | Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin. | 2015 Mar 1 |
1 |
| 35 |
25595658 | The neuroprotective role of metformin in advanced glycation end product treated human neural stem cells is AMPK-dependent. | 2015 May |
1 |
| 36 |
26056043 | Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2. | 2015 Aug 28 |
3 |
| 37 |
26111693 | [Effects of metformin on apoptosis induced by advanced glycation end-products and expressions of caspase-3, Bax and Bcl-2 in human dermal fibroblasts in vitro]. | 2015 Jun |
2 |
| 38 |
26266765 | Metformin and epithelial ovarian cancer therapeutics. | 2015 Oct |
1 |
| 39 |
26514477 | Evaluation of Effects of Metformin in Primary Ovarian Cancer Cells. | 2015 |
1 |
| 40 |
26688757 | Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells. | 2015 |
1 |
| 41 |
24577086 | Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling. | 2014 Feb 27 |
5 |
| 42 |
24612549 | Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma. | 2014 Mar 11 |
1 |
| 43 |
24858012 | Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells. | 2014 |
1 |
| 44 |
25419360 | Metformin inhibits cell growth by upregulating microRNA-26a in renal cancer cells. | 2014 |
1 |
| 45 |
23803693 | Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors. | 2013 Dec |
1 |
| 46 |
24378094 | [Metformin induces apoptosis in hepatocellular carcinoma Huh-7 cells in vitro and its mechanism]. | 2013 Oct |
1 |
| 47 |
23151022 | In vitro and in vivo anti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma. | 2012 Nov 14 |
1 |
| 48 |
21388661 | Induction of apoptosis by metformin in epithelial ovarian cancer: involvement of the Bcl-2 family proteins. | 2011 Jun 1 |
2 |
| 49 |
21776823 | Antidiabetic drug metformin induces apoptosis in human MCF breast cancer via targeting ERK signaling. | 2011 |
2 |