Pub. Date : 2015 Apr
PMID : 25492486
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin sensitizes hepatocellular carcinoma to arsenic trioxide-induced apoptosis by downregulating Bcl2 expression. | Metformin | BCL2 apoptosis regulator | Homo sapiens |
| 2 | Metformin is reported to decrease Bcl2 expression, and the purpose of this study was to verify whether metformin could potentiate the anti-HCC efficacy of ATO in vitro. | Metformin | BCL2 apoptosis regulator | Homo sapiens |
| 3 | Furthermore, this activity proceeded via a mechanism involving metformin-induced downregulation of Bcl2. | Metformin | BCL2 apoptosis regulator | Homo sapiens |