Title : Metformin sensitizes hepatocellular carcinoma to arsenic trioxide-induced apoptosis by downregulating Bcl2 expression.

Pub. Date : 2015 Apr

PMID : 25492486






3 Functional Relationships(s)
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Protein Name
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1 Metformin sensitizes hepatocellular carcinoma to arsenic trioxide-induced apoptosis by downregulating Bcl2 expression. Metformin BCL2 apoptosis regulator Homo sapiens
2 Metformin is reported to decrease Bcl2 expression, and the purpose of this study was to verify whether metformin could potentiate the anti-HCC efficacy of ATO in vitro. Metformin BCL2 apoptosis regulator Homo sapiens
3 Furthermore, this activity proceeded via a mechanism involving metformin-induced downregulation of Bcl2. Metformin BCL2 apoptosis regulator Homo sapiens