Pub. Date : 2009 Dec
PMID : 19002577
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ERalpha. | Tamoxifen | BCL2 apoptosis regulator | Homo sapiens |
2 | Antiestrogen (Tamoxifen and ICI 182,780) treatment increased Bcl-2 levels in both MCF-7 and -7B cells and led to the formation of acinar structures. | Tamoxifen | BCL2 apoptosis regulator | Homo sapiens |