Title : Effect of keratinocyte growth factor on cell viability in primary cultured human prostate cancer stromal cells.

Pub. Date : 2006 Jul

PMID : 16854582






1 Functional Relationships(s)
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1 Cell proliferation analysis indicated that tamoxifen or ICI 182,780 reduced cell viability in a dose-dependent manner; however, KGF prevented this inhibition, which further demonstrated KGF triggered anti-apoptotic machinery through activating Bcl-2 and phospho-Akt expression. Tamoxifen BCL2 apoptosis regulator Homo sapiens