Pub. Date : 2021 Aug 20
PMID : 34242793
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mechanistically, this protective autophagy is regulated by intracellular reactive oxygen species (ROS) accumulation, which triggers the downstream signals of JNK, Bcl-2 and Beclin-1. | Reactive Oxygen Species | BCL2 apoptosis regulator | Homo sapiens |
| 2 | Mechanistically, this protective autophagy is regulated by intracellular reactive oxygen species (ROS) accumulation, which triggers the downstream signals of JNK, Bcl-2 and Beclin-1. | Reactive Oxygen Species | BCL2 apoptosis regulator | Homo sapiens |
| 3 | More importantly, soft substrate-induced activation of ROS/JNK signaling promotes cell apoptosis through the mitochondrial pathway, whereas it increases protective autophagy by suppressing the interaction of Bcl-2 and Beclin-1. | Reactive Oxygen Species | BCL2 apoptosis regulator | Homo sapiens |