gemcitabine

BCL2 associated X, apoptosis regulator ; Homo sapiens







32 Article(s)
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1 34089613 Hypericin-mediated photodynamic therapy enhances gemcitabine induced Capan-2 cell apoptosis via inhibiting NADPH level. 2022 Apr 20 1
2 32522594 TIMP1 down-regulation enhances gemcitabine sensitivity and reverses chemoresistance in pancreatic cancer. 2021 Jul 3
3 33531986 The COL11A1/Akt/CREB signaling axis enables mitochondrial-mediated apoptotic evasion to promote chemoresistance in pancreatic cancer cells through modulating BAX/BCL-2 function. 2021 1
4 32599367 (3E,5E)-3,5-Bis(pyridin-3-methylene)-tetrahydrothiopyran-4-one enhances the inhibitory effect of gemcitabine on pancreatic cancer cells. 2020 Aug 1
5 31521140 The synergism of Clinacanthus nutans Lindau extracts with gemcitabine: downregulation of anti-apoptotic markers in squamous pancreatic ductal adenocarcinoma. 2019 Sep 14 1
6 30308458 Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1). 2018 Dec 1
7 30454541 [Microwave Hyperthermia Combined with Gemcitabine Inhibits Proliferation 
and Induces Apoptosis of Human Lung Squamous Carcinoma Cells]. 2018 Nov 20 1
8 28055291 Metuzumab enhanced chemosensitivity and apoptosis in non-small cell lung carcinoma. 2017 Jan 2 1
9 28797284 Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2). 2017 Aug 10 1
10 27459907 Coix seed emulsion synergistically enhances the antitumor activity of gemcitabine in pancreatic cancer through abrogation of NF-κB signaling. 2016 Sep 1
11 25344906 Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer. 2015 Apr 1
12 25833690 Gemcitabine impacts differentially on bladder and kidney cancer cells: distinct modulations in the expression patterns of apoptosis-related microRNAs and BCL2 family genes. 2015 May 1
13 25880226 pERK1/2 silencing sensitizes pancreatic cancer BXPC-3 cell to gemcitabine-induced apoptosis via regulating Bax and Bcl-2 expression. 2015 Feb 21 7
14 24014050 The role of Bax and Bcl-2 in gemcitabine-mediated cytotoxicity in uveal melanoma cells. 2014 Feb 1
15 24216611 MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX. 2014 Feb 3
16 24619961 Berbamine enhances the antineoplastic activity of gemcitabine in pancreatic cancer cells by activating transforming growth factor-β/Smad signaling. 2014 May 1
17 24804820 The cytoprotective role of gemcitabine-induced autophagy associated with apoptosis inhibition in triple-negative MDA-MB-231 breast cancer cells. 2014 Jul 1
18 24998655 [Down-regulation of Notch1 by small interfering RNA enhances chemosensitivity to gemcitabine in pancreatic cancer cells through activating apoptosis activity]. 2014 May 1
19 25242370 Enhancement of the effects of gemcitabine against pancreatic cancer by oridonin via the mitochondrial caspase-dependent signaling pathway. 2014 Dec 5
20 22159556 Emodin reverses gemcitabine resistance in pancreatic cancer cells via the mitochondrial apoptosis pathway in vitro. 2012 Apr 1
21 22573342 Induction of pancreatic cancer cell apoptosis and enhancement of gemcitabine sensitivity by RAP80 siRNA. 2012 Aug 2
22 22679728 [Emodin combined gemcitabine inhibited the growth of pancreatic cancer in vitro and in vivo and its mechanisms study]. 2012 May 3
23 21305255 Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis. 2011 May 1
24 21570961 β2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction. 2011 Aug 31 1
25 20302733 [An experimental study of gemcitabine inducing pancreatic cancer cell apoptosis potentiated by nuclear factor-kappa B P65 siRNA]. 2010 Jan 15 1
26 19763526 Lysosomal ceramide mediates gemcitabine-induced death of glioma cells. 2009 Nov 1
27 17984977 Telomerase transcriptional targeting of inducible Bax/TRAIL gene therapy improves gemcitabine treatment of pancreatic cancer. 2008 Feb 2
28 16162974 Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria. 2005 Oct 2
29 14750167 Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis. 2004 Mar 20 1
30 12138244 Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes. 2002 1
31 10803919 The role of p53 in gemcitabine-mediated cytotoxicity and radiosensitization. 2000 2
32 10341297 Induction of growth inhibition and apoptosis in pancreatic cancer cells by auristatin-PE and gemcitabine. 1999 Jun 1