Pub. Date : 2014 Dec
PMID : 25242370
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Western blot and quantitative polymerase chain reaction analyses demonstrated that the expression levels of the anti-apoptotic gene Bcl-2 and the Bcl-2/Bax ratio in the oridonin and the oridonin plus gemcitabine groups were significantly downregulated as compared with the gemcitabine treatment and control groups. | gemcitabine | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | The results suggested that oridonin improved the anti-tumor effects of gemcitabine through the enhancement of gemcitabine-induced apoptosis.This mechanism may be through the downregulation of Bcl-2 expression and the upregulation of Bax expression, resulting in the reduction of the Bcl-2/Bax ratio. | gemcitabine | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 3 | The results suggested that oridonin improved the anti-tumor effects of gemcitabine through the enhancement of gemcitabine-induced apoptosis.This mechanism may be through the downregulation of Bcl-2 expression and the upregulation of Bax expression, resulting in the reduction of the Bcl-2/Bax ratio. | gemcitabine | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 4 | The results suggested that oridonin improved the anti-tumor effects of gemcitabine through the enhancement of gemcitabine-induced apoptosis.This mechanism may be through the downregulation of Bcl-2 expression and the upregulation of Bax expression, resulting in the reduction of the Bcl-2/Bax ratio. | gemcitabine | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 5 | The results suggested that oridonin improved the anti-tumor effects of gemcitabine through the enhancement of gemcitabine-induced apoptosis.This mechanism may be through the downregulation of Bcl-2 expression and the upregulation of Bax expression, resulting in the reduction of the Bcl-2/Bax ratio. | gemcitabine | BCL2 associated X, apoptosis regulator | Homo sapiens |