Title : Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2).

Pub. Date : 2017 Aug 10

PMID : 28797284






1 Functional Relationships(s)
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1 Western blot results demonstrated that gambogic acid sensitized gemcitabine-induced apoptosis by enhancing the expression of cleaved caspase-3, cleaved caspase-9, cleaved-PARP, and Bax, and reducing the expression of Bcl-2. gemcitabine BCL2 associated X, apoptosis regulator Homo sapiens