Vorinostat

BCL2 associated X, apoptosis regulator ; Homo sapiens







25 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30717701 Evaluation of the antioxidant effects of different histone deacetylase inhibitors (HDACis) on human lens epithelial cells (HLECs) after UVB exposure. 2019 Feb 4 1
2 30923410 The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells. 2019 Feb 28 1
3 31100944 Application of Electric Cell-Substrate Impedance Sensing to Investigate the Cytotoxic Effects of Andrographolide on U-87 MG Glioblastoma Cell Migration and Apoptosis. 2019 May 16 1
4 31406244 FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma. 2019 Oct 2
5 30091530 ING5-mediated antineuroblastoma effects of suberoylanilide hydroxamic acid. 2018 Sep 1
6 28267674 The effects of SAHA on radiosensitivity in pancreatic cancer cells by inducing apoptosis and targeting RAD51. 2017 May 1
7 29212192 Vorinostat and metformin sensitize EGFR-TKI resistant NSCLC cells via BIM-dependent apoptosis induction. 2017 Nov 7 1
8 26050346 Sensitization of suberoylanilide hydroxamic acid (SAHA) on chemoradiation for human cervical cancer cells and its mechanism. 2015 3
9 24814395 Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA. 2014 Aug 28 1
10 25139025 Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines. 2014 Dec 1
11 25261655 Effects and mechanism of suberoylanilide hydroxamic acid on the proliferation and apoptosis of human hepatoma cell line Bel-7402. 2014 Jul-Sep 2
12 25546354 Effects of suberoylanilide hydroxamic acid (SAHA) combined with paclitaxel (PTX) on paclitaxel-resistant ovarian cancer cells and insights into the underlying mechanisms. 2014 1
13 22086447 Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage. 2013 Feb 1
14 24278362 Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression. 2013 1
15 21652541 Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters. 2011 Jun 15 1
16 21472287 Synergistic induction of apoptosis in HeLa cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitor SAHA. 2010 Jul-Aug 1
17 18694296 Histone deacetylase inhibitors promote apoptosis and senescence in human mesenchymal stem cells. 2009 May 1
18 18166465 Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. 2008 Mar 15 1
19 18310471 Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents. 2008 Jun 1
20 18765530 Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 2008 Sep 1 1
21 18065490 Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells. 2007 Dec 1
22 16550602 The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL. 2006 Aug 15 1
23 15625278 Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change. 2005 Apr 1
24 15897598 Novel histone deacetylase inhibitors in the treatment of thyroid cancer. 2005 May 15 1
25 16297208 Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action. 2005 Nov 2