Pub. Date : 2015
PMID : 26050346
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bax mRNA and protein expressions were higher but Ku70 mRNA and protein expressions were lower in SAHA combined with radiotherapy group than in radiotherapy alone group (p < 0.05). | Vorinostat | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | CONCLUSION: SAHA promotes SiHa apoptosis in chemotherapy through up-regulation of mRNA and protein of p21 and Bax which leads to cell cycle arrest in G0/G1 phase. | Vorinostat | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 3 | Low dose of SAHA promotes SiHa apoptosis and inhibits cell repair in radiotherapy through Bax up-regulation and Ku70 down-regulation. | Vorinostat | BCL2 associated X, apoptosis regulator | Homo sapiens |