Title : Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts.

Pub. Date : 2008 Mar 15

PMID : 18166465






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 2+SAHA treatment effectively down-regulated cyclin D1 and cdk4, and up-regulated pro-differentiation markers cytokeratins 8/18 and pro-apoptotic Bad and Bax. Vorinostat BCL2 associated X, apoptosis regulator Homo sapiens