Oxaliplatin

KRAS proto-oncogene, GTPase ; Homo sapiens







55 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33468383 Predictive value of KRAS mutation and excision repair cross-complementing 1 (ERCC1) protein overexpression in patients with colorectal cancer administered FOLFOX regimen. 2021 May 3
2 34330763 Statin-mediated inhibition of RAS prenylation activates ER stress to enhance the immunogenicity of KRAS mutant cancer. 2021 Jul 2
3 32062671 Efficacy of Oxaliplatin/5-Fluorouracil/Capecitabine-Cetuximab Combination Therapy and Its Effects on K-Ras Mutations in Advanced Colorectal Cancer. 2020 Feb 16 2
4 32163218 Curcumin β-D-glucuronide exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity in vivo. 2020 May 2
5 32271417 Influence of KRAS mutations on clinical outcome in patients with curatively resected stage III colon cancer treated with adjuvant chemotherapy. 2020 Mar 1
6 32444490 Metformin selectively inhibits metastatic colorectal cancer with the KRAS mutation by intracellular accumulation through silencing MATE1. 2020 Jun 9 1
7 33120790 Trifluridine/tipiracil in combination with local therapy may be a favorable option for refractory metastatic colorectal cancer patients: A case report. 2020 Oct 23 1
8 30307354 Afatinib treatment for her-2 amplified metastatic colorectal cancer based on patient-derived xenograft models and next generation sequencing. 2019 1
9 30422156 Continuation of Bevacizumab vs Cetuximab Plus Chemotherapy After First Progression in KRAS Wild-Type Metastatic Colorectal Cancer: The UNICANCER PRODIGE18 Randomized Clinical Trial. 2019 Jan 1 1
10 30739089 A case of panitumumab containing chemotherapy causing interstitial lung disease: early recognition and treatment resulting in a good outcome. 2019 Feb 9 1
11 30792807 Anticancer response to disulfiram may be enhanced by co-treatment with MEK inhibitor or oxaliplatin: modulation by tetrathiomolybdate, KRAS/BRAF mutations and c-MYC/p53 status. 2019 1
12 28229371 Overall Survival and Metastasis Resections in Patients with Metastatic Colorectal Cancer Using Electronic Medical Records. 2018 Sep 1
13 28040715 Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer. 2017 Jan 1
14 28418176 Panitumumab-Conjugated Pt-Drug Nanomedicine for Enhanced Efficacy of Combination Targeted Chemotherapy against Colorectal Cancer. 2017 Jul 1
15 26515332 KRAS polymorphisms are associated with survival of CRC in Chinese population. 2016 Apr 1
16 27143148 Cost-Effectiveness Analysis of Different Sequences of the Use of Epidermal Growth Factor Receptor Inhibitors for Wild-Type KRAS Unresectable Metastatic Colorectal Cancer. 2016 Jun 1
17 27155924 [KRAS mutation does not influence oxaliplatin or irinotecan efficacy, in association with bevacizumab, in first line treatment of metastatic colorectal cancer]. 2016 Jun 1
18 27229742 A Phase II Study of Third-Line Combination Chemotherapy with Bevacizumab Plus S-1 for Metastatic Colorectal Cancer with Mutated KRAS (SAVIOR Study). 2016 1
19 28101205 Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation. 2016 Dec 1
20 28356789 Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience. 2016 1
21 24889488 KRAS mutation is associated with worse prognosis in stage III or high-risk stage II colon cancer patients treated with adjuvant FOLFOX. 2015 Jan 1
22 25553091 ERCC1 Induction after Oxaliplatin Exposure May Depend on KRAS Mutational Status in Colorectal Cancer Cell Line: In Vitro Veritas. 2015 3
23 25870609 Global impact of KRAS mutation patterns in FOLFOX treated metastatic colorectal cancer. 2015 2
24 25937522 FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer. 2015 Jul 1
25 25998052 Cetuximab-oxaliplatin-liposomes for epidermal growth factor receptor targeted chemotherapy of colorectal cancer. 2015 Jul 28 1
26 26525741 High SLFN11 expression predicts better survival for patients with KRAS exon 2 wild type colorectal cancer after treated with adjuvant oxaliplatin-based treatment. 2015 Nov 2 2
27 23821376 Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT. 2014 Jun 2
28 24468885 Effect of simvastatin plus cetuximab/irinotecan for KRAS mutant colorectal cancer and predictive value of the RAS signature for treatment response to cetuximab. 2014 Jun 1
29 24505265 Oxaliplatin-based chemotherapy is more beneficial in KRAS mutant than in KRAS wild-type metastatic colorectal cancer patients. 2014 8
30 24764664 Anti-EGFR and anti-VEGF agents: important targeted therapies of colorectal liver metastases. 2014 Apr 21 2
31 24772300 KRAS mutation in patients with metastatic colorectal cancer does not preclude benefit from oxaliplatin-or irinotecan-based treatment. 2014 May 1
32 24960403 Phase II study of gemcitabine, oxaliplatin in combination with panitumumab in KRAS wild-type unresectable or metastatic biliary tract and gallbladder cancer. 2014 Jul 29 2
33 25818736 A meta analysis of cetuximab plus oxaliplatin based chemotherapy regimen for metastatic colorectal cancer. 2014 Mar 2
34 23175150 KRAS mutational status affects oxaliplatin-based chemotherapy independently from basal mRNA ERCC-1 expression in metastatic colorectal cancer patients. 2013 Jan 15 3
35 23689915 Prospective phase II study of neoadjuvant FOLFOX6 plus cetuximab in patients with colorectal cancer and unresectable liver-only metastasis. 2013 Jul 1
36 23730417 Oxaliplatin-based Chemotherapy Might Provide Longer Progression-Free Survival in KRAS Mutant Metastatic Colorectal Cancer. 2013 Jun 6
37 23822592 Which is false: oxaliplatin or fluoropyrimidine? An analysis of patients with KRAS wild-type metastatic colorectal cancer treated with first-line epidermal growth factor receptor monoclonal antibody. 2013 Oct 2
38 22740893 Good response to leucovorin and fluorouracil plus oxaliplatin and cetuximab therapy in a patient with metastatic ascending colon cancer harboring a KRAS p.G13D mutation. 2012 Feb 1
39 22876876 Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group. 2012 Aug 9 3
40 22909976 K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy. 2012 Nov 3
41 22948721 Impact of the specific mutation in KRAS codon 12 mutated tumors on treatment efficacy in patients with metastatic colorectal cancer receiving cetuximab-based first-line therapy: a pooled analysis of three trials. 2012 1
42 23209813 KRAS mutation is a predictor of oxaliplatin sensitivity in colon cancer cells. 2012 6
43 23226426 No survival benefit from adding cetuximab or panitumumab to oxaliplatin-based chemotherapy in the first-line treatment of metastatic colorectal cancer in KRAS wild type patients: a meta-analysis. 2012 1
44 23268018 [Clinical outcomes in refractory colorectal cancer patients with wild-type K-ras treated with bevacizumab and oxaliplatin-based chemotherapy as a first-line treatment]. 2012 Nov 2
45 20972872 Clinical impact of K-ras mutation in colorectal cancer patients treated with adjuvant FOLFOX. 2011 Aug 1
46 21228335 Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 2011 Jul 2
47 21508389 Combined KRAS and TP53 mutation status is not predictive in CAPOX-treated metastatic colorectal cancer. 2011 Apr 2
48 21635994 Cost-effectiveness of targeted therapy with cetuximab in patients with K-ras wild-type colorectal cancer presenting with initially unresectable metastases limited to the liver in a German setting. 2011 Apr 1
49 21894049 KRAS mutation in metastatic pancreatic ductal adenocarcinoma: results of a multicenter phase II study evaluating efficacy of cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line therapy. 2011 1
50 20354524 Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. 2010 Apr 13 3