Title : Oxaliplatin-based Chemotherapy Might Provide Longer Progression-Free Survival in KRAS Mutant Metastatic Colorectal Cancer.

Pub. Date : 2013 Jun

PMID : 23730417






6 Functional Relationships(s)
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1 Oxaliplatin-based Chemotherapy Might Provide Longer Progression-Free Survival in KRAS Mutant Metastatic Colorectal Cancer. Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens
2 In patients who received first-line oxaliplatin-based regimens, the PFS was significantly longer in KRAS mutant patients (N = 32) than that in KRAS wild-type patients (N = 51). Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens
3 In patients who received first-line oxaliplatin-based regimens, the PFS was significantly longer in KRAS mutant patients (N = 32) than that in KRAS wild-type patients (N = 51). Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens
4 In multivariate analyses, KRAS mutation remains an independent predictive factor for longer PFS in first-line oxaliplatin-based regimens. Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens
5 In conclusion, oxaliplatin-based chemotherapy in KRAS mutant mCRC might result in longer PFS than in KRAS wild-type mCRC. Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens
6 In conclusion, oxaliplatin-based chemotherapy in KRAS mutant mCRC might result in longer PFS than in KRAS wild-type mCRC. Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens