Title : Statin-mediated inhibition of RAS prenylation activates ER stress to enhance the immunogenicity of KRAS mutant cancer.

Pub. Date : 2021 Jul

PMID : 34330763






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Combination therapy using statin and oxaliplatin, an ICD inducer, significantly enhanced the immunogenicity of KRAS mut tumors and promoted tumor-specific immunity in syngeneic and genetically engineered KRAS mut tumor models. Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens
2 Combination therapy using statin and oxaliplatin, an ICD inducer, significantly enhanced the immunogenicity of KRAS mut tumors and promoted tumor-specific immunity in syngeneic and genetically engineered KRAS mut tumor models. Oxaliplatin KRAS proto-oncogene, GTPase Homo sapiens