Ibuprofen

prostaglandin-endoperoxide synthase 1 ; Homo sapiens







22 Article(s)
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1 25385584 Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs. 2014 Nov 25 2
2 22882748 Influence of non-steroidal anti-inflammatory drugs on antiplatelet effect of aspirin. 2013 Feb 2
3 24027742 An Interesting Observation of PDA Closure with Oral Paracetamol in Preterm Neonates. 2013 Jan 1
4 24255997 Mitigating the cardiovascular and renal effects of NSAIDs. 2013 Dec 1
5 21602044 Methyl-monofluorination of ibuprofen selectively increases its inhibitory activity toward cyclooxygenase-1 leading to enhanced analgesic activity and reduced gastric damage in vivo. 2011 Jun 15 2
6 20664853 Acyclic triaryl olefins possessing a sulfohydroxamic acid pharmacophore: synthesis, nitric oxide/nitroxyl release, cyclooxygenase inhibition, and anti-inflammatory studies. 2010 Sep 21 2
7 17944992 Pyrazolinone analgesics prevent the antiplatelet effect of aspirin and preserve human platelet thromboxane synthesis. 2008 Jan 2
8 18036557 p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells. 2008 Jan 25 1
9 16675319 Potential for drug-drug interactions in patients taking analgesics for mild-to-moderate pain and low-dose aspirin for cardioprotection. 2006 May 8 2
10 16730702 Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment. 2006 Jul 1 2
11 15705740 Cellular mechanisms of acetaminophen: role of cyclo-oxygenase. 2005 Apr 1
12 15892673 The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. 2005 1
13 15369391 Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints. 2004 Sep 23 1
14 12852704 Valdecoxib: a review. 2003 Mar 2
15 12398900 On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1. 2002 Oct 25 2
16 11318639 Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. 2001 May 1 1
17 11755111 Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin. 2001 Dec 15 1
18 10966456 Cyclooxygenases: structural, cellular, and molecular biology. 2000 1
19 10477832 PGHS-2 inhibitors, NS-398 and DuP-697, attenuate the inhibition of PGHS-1 by aspirin and indomethacin without altering its activity. 1999 Aug 25 1
20 9351505 Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases. 1997 Oct 3
21 8626626 Photolabeling of prostaglandin endoperoxide H synthase-1 with 3-trifluoro-3-(m-[125I]iodophenyl)diazirine as a probe of membrane association and the cyclooxygenase active site. 1996 Apr 26 1
22 8831731 Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells. 1996 Oct 11 1