Polyamines

ornithine decarboxylase 1 ; Homo sapiens







668 Article(s)
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1 35100927 Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer. 2022 Jul 6
2 35177822 YAP/TAZ drives cell proliferation and tumour growth via a polyamine-eIF5A hypusination-LSD1 axis. 2022 Mar 1
3 35209071 Inhibitory Effect of Ursolic Acid on the Migration and Invasion of Doxorubicin-Resistant Breast Cancer. 2022 Feb 14 1
4 35486659 Polyamine biosynthesis and eIF5A hypusination are modulated by the DNA tumor virus KSHV and promote KSHV viral infection. 2022 Apr 2
5 35541910 Downregulation of MTAP promotes Tumor Growth and Metastasis by regulating ODC Activity in Breast Cancer. 2022 2
6 32597331 Structure based design of inhibitory peptides targeting ornithine decarboxylase dimeric interface and in vitro validation in human retinoblastoma Y79 cells. 2021 Sep 3
7 33305406 Oesophageal squamous cell carcinoma-associated IL-33 rewires macrophage polarization towards M2 via activating ornithine decarboxylase. 2021 Feb 1
8 33432662 Regulation of polyamine homeostasis through an antizyme citrullination pathway. 2021 Aug 5
9 33452997 Rice yellow stunt virus activates polyamine biosynthesis to promote viral propagation in insect vectors by disrupting ornithine decarboxylase antienzyme function. 2021 Sep 3
10 33531815 Role of Antizyme Inhibitor Proteins in Cancers and Beyond. 2021 4
11 33579942 Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas. 2021 Feb 12 2
12 33777791 Dual Inhibition of Ornithine Decarboxylase and A1 Adenosine Receptor Efficiently Suppresses Breast Tumor Cells. 2021 4
13 33918978 A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma. 2021 Apr 9 2
14 33991460 TRPC1-mediated Ca2+ signaling enhances intestinal epithelial restitution by increasing α4 association with PP2Ac after wounding. 2021 May 1
15 34046926 Antizyme inhibitor 2 (AZIN2) associates with better prognosis of head and neck minor salivary gland adenoid cystic carcinoma. 2021 Aug 2
16 34055746 The First Insight Into the Supramolecular System of D,L-α-Difluoromethylornithine: A New Antiviral Perspective. 2021 2
17 34095122 Arginine Metabolism and Its Potential in Treatment of Colorectal Cancer. 2021 1
18 34129075 Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma. 2021 Oct 2
19 34252566 The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors. 2021 Sep 4
20 34472307 [Optimization of a cucurbit[6]uril-based real-time label-free method for analyzing the activity of ornithine decarboxylase]. 2021 Aug 25 2
21 34522028 The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme. 2021 Sep 14 1
22 34529197 Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase. 2021 Nov 3
23 34560100 Discovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis. 2021 Oct 2
24 34796899 Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane. 2021 Dec 10 4
25 30972602 Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure. 2020 Feb 2
26 31503278 Association Between Plasma Diacetylspermine and Tumor Spermine Synthase With Outcome in Triple-Negative Breast Cancer. 2020 Jun 1 1
27 32046633 Characterizing lineage-specific evolution and the processes driving genomic diversification in chordates. 2020 Feb 11 1
28 32094585 Ornithine capture by a translating ribosome controls bacterial polyamine synthesis. 2020 Apr 1
29 32119868 The Polyamine Putrescine Promotes Human Epidermal Melanogenesis. 2020 Oct 1
30 32123240 Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1. 2020 Mar 2 2
31 32139506 Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy. 2020 May 8 1
32 32181810 Translation efficiency affects the sequence-independent +1 ribosomal frameshifting by polyamines. 2020 Aug 1 1
33 32767470 The rational discovery of multipurpose inhibitors of the ornithine decarboxylase. 2020 Sep 4
34 32786875 Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells. 2020 Aug 28 2
35 33002680 Polyamine regulation of porcine reproductive and respiratory syndrome virus infection depends on spermidine-spermine acetyltransferase 1. 2020 Nov 3
36 33037185 FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer. 2020 Oct 9 3
37 33292222 Polyamines and related signaling pathways in cancer. 2020 Nov 5 1
38 29436980 Virtual screening of natural inhibitors targeting ornithine decarboxylase with pharmacophore scaffolding of DFMO and validation by molecular dynamics simulation studies. 2019 Feb 3
39 30642111 Inhibition of Polyamine Biosynthesis Reverses Ca2+ Channel Remodeling in Colon Cancer Cells. 2019 Jan 13 2
40 30768610 Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer. 2019 2
41 30842655 p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis. 2019 Mar 2
42 31064849 PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness. 2019 Jul 1 3
43 31239700 ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma. 2019 2
44 31362455 Purification and Characterization of Ornithine Decarboxylase from Aspergillus terreus; Kinetics of Inhibition by Various Inhibitors. 2019 Jul 29 3
45 31509528 Polyamine biosynthesis in Xenopus laevis: the xlAZIN2/xlODC2 gene encodes a lysine/ornithine decarboxylase. 2019 2
46 32256343 Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells. 2019 1
47 28971766 Ornithine Decarboxylase Inhibition: A Strategy to Combat Various Diseases. 2018 1
48 29108956 The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase. 2018 Mar 4
49 29241071 Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma. 2018 Feb 4
50 29419804 Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases. 2018 Feb 8 2