Title : Oesophageal squamous cell carcinoma-associated IL-33 rewires macrophage polarization towards M2 via activating ornithine decarboxylase.

Pub. Date : 2021 Feb

PMID : 33305406






1 Functional Relationships(s)
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1 Mechanistically, IL-33 induces M2-like macrophage polarization by activating ODC, a key enzyme that catalyses the synthesis of polyamines. Polyamines ornithine decarboxylase 1 Homo sapiens